Latest database descriptions

General objective: The objective of this multi-disciplinary project (neurology, pharmacology, epidemiology etc.) is to prospectively gather data in a population of outpatients with Parkinson's disease identified through a regional network of hospital neurologists and independent physicians, concerning the onset and progression of motor signs (tremor, akinesia, rigidity, motor complications, freezing, falls, dysarthria ...) and non-motor signs (pain, anxiety and depressive symptoms, autonomic dysfunction, sleep disorders, dementia, apathy, fatigue ...) of PD using validated scales. We will also gather data on quality of life, treatment (care sought and consumption of medication), morbidity and mortality within the same population. Secondary objective: To develop a biobank in the second phase based on phenotypic and pharmacological characterisations outlined in the COPARK population

General objective: to form the largest prospective cohort of melanoma patients in Europe with a blood and tissue biobank Secondary objective: to form a research team made up of clinicians, pathologists, geneticists and basic science researchers, in order to obtain high quality research responsiveness

To study cancer mortality in a cohort of French nuclear workers from contracting companies. Secondary objective: to improve knowledge of the carcinogenic effects of low-level doses of ionizing radiation and multiple exposure.

General objective: Assessment of bone architecture, age-related changes, determinants and relationship to bone fragility.