Latest database descriptions

General objective: to describe the natural history of hepatocellular carcinoma (HCC) in alcoholic cirrhosis. Secondary objectives: - to establish a comparison with the national cohort - to establish a comparison with the national cohort of viral cirrhosis ANRS CO12 CirVir - to form an ancillary study database from biological resources taken at enrolment and afterwards annually as well as associated clinical data.

General objective: to study whether or not different forms of hormonal contraception contribute to the risk of venous thrombosis recurrence for women at high risk of venous thromboembolism.

To specify the physiopathological processes resulting in alcohol-related brain abnormalities and neuropsychological disorders. To identify the factors explaining the heterogeneity of alcohol-related brain abnormalities and neuropsychological disorders. To investigate the neural substrates of Theory of Mind deficits in alcohol dependent patients with no neurological complications. To examine the brain mechanisms underlying neuropsychological recovery in AL patients with abstinence.

To form a cohort of clinically well evaluated patients with autistic disorders. To identify genetic factors involved in autism spectrum disorders. To establish genotype-phenotype correlations.