Latest database descriptions

Chronic Kidney Disease - Renal Epidemiology and Information Network

May 23 2025

The CKD-REIN cohort will provide a research platform to address key questions regarding a number of determinants and biomarkers associated with adverse CKD outcomes and to assess clinical practices and costs in patients selected at random from a representative sample of various types of nephrology consultations. In addition, it will meet the objectives of the starting international CKD Outcomes and Practice Patterns Study (CKDopps) designed principally to identify best treatment practices in patients with advanced CKD in several countries, including France.
The objectives of the CKD-REIN study are:
(1) to study a set of social, environmental, behavioral, clinical, and genetic factors, and their interactions in relation with the outcomes of CKD and its complications, including progression to ESRD and mortality, as well as the onset of several relevant acute and chronic clinical events : acute kidney injury, infections; cardiovascular diseases, cognitive decline, bone disease, and cancer ;
(2) to assess several new biomarkers to predict adverse outcomes of CKD and its complications;
(3) to evaluate the associations of provider practices (management of hypertension and of CKD complications such as anemia, nutritional abnormalities, and bone mineral disorder; timing of dialysis initiation and transplant wait-listing) with achievement of clinical practice guidelines, clinical outcomes (survival, ESRD, hospital admissions) and patient-reported outcomes (QoL, satisfaction).
(4) to evaluate the associations of health care organization (e.g., multidisciplinary team, care network) and clinic services (e.g., for nutrition, educational programs) with clinical and patient-reported outcomes, and achievement of clinical practice guidelines;
(5) to estimate the relative cost-effectiveness of different provider practices and clinic services.
(6) to estimate the CKD incidence and prevalence in nephrology healthcare practices in France, depending on age, sex, social status, diabetes status, and depending on the stage and type of CKD.

Evolutions et relations en Santé au travail

May 16 2025

provide collective data concerning the working conditions and health of employees

Cryoconservation during allogeneic hematopoietic Stem cell transplantation

May 16 2025

The goal of CryoStem is to create a national, multicenter, prospectie, longitudinal, standardized HSCT human-sample collection (derived from adult and pediatric patients) with the purpose of enabling better characterization and prediction of HSCT complications occurence and outcome, including GvHD.
CryoStem has generated a French network involving all the French transplant units, adult and pediatric and 28 Biological Resources Centres. Only in a network such as this may the full potential be realized of having concrete and effective interactions between scientists with top knowledge in specific areas and physicians. CryoStem fosters interactions among internationally recognized experts in advanced biotechnology (genomics,transcriptomics, proteomics, and flow cytometry).
Altogether, CryoStem provides a structured approach for a range of different research activities, bringing together leading-edge researchers who can access documented biological (CryoStem) and clinical (ProMISe) samples from transplanted patients in order to better characterize and predict HSCT complications.

National Multicentre, Multidisciplinary, Clinical-Biological Database for Kidney Cancer

May 14 2025

The main objective is to rely on a common multidisciplinary and unifying tool (UroCCR Database), to develop a national network of medical and scientific activity focused on therapeutic treatment and applied research for kidney cancer.

The complementarity of skills and culture of a strong translational connection, collaboration with cancer registries and the creation of a collection of multicentre, annotated biological samples allow ancillary research projects to be carried out as part of the UroCCR network, aimed at economic and lead time efficiency.

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