Latest database descriptions

Main Objective: To identify, through the creation of a clinico-biological, prospective, multicentric French database, the clinical, biological and tumour factors linked to anti-tumour therapy resistance in patients treated for stage I to IV oesophageal or stomach cancer. Secondary Objectives: - To assess the impact of different current therapeutic strategies for recurrence, survival and quality of life. - To identify predictive factors for patient treatment resistance in order to identify the most efficient and least toxic therapeutic combination. - To describe individual, social and behavioural characteristics of patients included in the study. - To identify individual and collective determinants that influence possible access to care and initiation of treatment. - To identify new prognostic and predictive relapse factors.

The French National Occupational Diseases Surveillance and Prevention Network (RNV3P) groups together the 32 Occupational Disease Consultation Centres (CCPPs) in mainland France and a sample of 10 occupational health services (SSTs) associated with the network. This network aims to collect data from each consultation in a permanent national database on occupational diseases (patient’s demographic data, diseases, exposures, business sector and profession). The RNV3P has two interrelated components: "RNV3P-CCPP" and "RNV3P-SST". The former is a surveillance system for CCPP patient consultations while the latter is a survelliance system for the working population. One of the original aims of RNV3P is to record CCPP expertise on the causal nature of relations between occupational exposure and diseases observed in patients. It is up to the network's university-hospital experts to investigate the diseases and attribute them, if necessary, to an occupational origin (this causality is also registered in the database). The RNV3P is not a health surveillance system that gives a representative picture of actual disease frequency in a given field. Its main objectives are to identify and describe at-risk occupational situations in France, and to research new etiologies and emerging occupational health risks. As a network operator, ANSES is responsible for coordinating all activities associated with the network and to participate in related scientific work in partnership with the State Health Insurance Fund for Salaried Workers (CNAM-TS), the Central Health and Social Security Insurance Fund for Agricultural Employees (CCMSA), the French Institute for Public Health Surveillance (InVS), and the French Occupational Medicine Society (SFMT).

Surveillance and assessment of the risk of immune thrombocytopenic purpura associated with drug or vaccine use in real life situations.

Objectives in terms of public health:
1) Monitor prevalence rates of severe childhood disabilities over time in a defined geographical area (population-based register)
2) Describe characteristics of these disabilities, medical conditions associated with the main impairment
3) Describe care, assistance and schooling of these children
3) Assist in the planning of medical and social offering suitable for such children (availability of specialized care facilities, home care and outpatient care)

Research objectives :
1) Progress in the etiological knowledge and study risk factors especially perinatal risk factors
2) Assess the consequences of preventive or screening measures implemented during pregnancy
3) Describe and understand factors associated with better participation and quality of life of disabled children