Latest database descriptions

The objectives of the study are, from a cohort survey on a population of patients suffering from congenital heart diseases:
1) estimate the prevalence, the time of diagnosis, the medical and surgical care of congenital heart diseases infected newborns
2) Evaluate the mortality, the morbidity and future neural development of these children
3) Identify factors linked to short and long term prognosis, including the impact of the time of diagnosis, medical and surgical care of the children, as well as the role of the channels of health care, and socio-economic factors.

Evaluate the safety and effectiveness of the treatment via recombinant human growth hormone (Humatrope) using observation data.

Children with congenital heart disease frequently undergo cardiac catheterization procedures for diagnostic or treatment purposes. Despite the clear clinical benefit to the patient, the complexity of these procedures may result in high cumulative radiation exposure. Given children's greater sensitivity to radiation and the longer life span during which radiation health effects can develop, an epidemiological cohort study, named Coccinelle (Cohorte sur le risque de cancer après cardiologie interventionnelle pédiatrique) is being launched in France to evaluate the risks of leukaemia and solid cancers in this specific population.

Studying in detail the immunological mechanisms of atherosclerosis after transplantation via immunomonitoring cohort of renal transplant patients