Latest database descriptions

To study the impact on pregnancy (prematurity, delayed intrauterine growth, birth defects) and postnatal neurological development from exposure (prenatal and childhood) to organochlorine pollutants (mainly chlordecone) in Guadeloupe.

To evaluate current risk factors that fit today's practice and long-term prognosis for different anatomical and clinical forms of symptomatic thromboembolism (proximal and distal deep vein thrombosis, superficial venous thrombosis, pulmonary embolism) Follow-up covers recurrent VTE, arterial thrombotic events (coronary, CVA, PAD), onset of cancer, haemorrhagic stroke, post-thrombotic syndrome and death.

To correlate received doses and volume of irradiated normal tissues in the cohort of patients who underwent overexposure of varying degrees, as well as complications observed with biologic, phenotypic and genetic data. The incidence and severity of iatrogenic effects and sequelae of radiotherapy (according to soma-lent and CTCAE scales) are correlated using a precise reconstruction of actual irradiation dosimetry received by each patient (total radiation dose prescribed and issued by daily controls) according to technical dossier data and system treatment planning. Secondary objective: to gather biological collections from blood samples (serum bank, DNA bank, lymphocytes) to correlate iatrogenic complications and radiation doses to normal tissues with biologic, phenotypic and genetic data. These collections will be used to: - identify factors associated with susceptibility to radiation-induced complications in normal tissues; - study radiation fibrosis biology; - study normal tissue radiosensitivity: rectal wall; - study the biological control dose-response relationship for prostate adenocarcinoma; - implement radiogenic fibrosis treatment protocols.

General objective: to evaluate whether psychiatric, addictive and psychological factors reported on waiting lists have an impact on medico-surgical outcome for liver and kidney transplantations. Secondary objective: to evaluate whether psychiatric, addictive and psychological factors reported after transplant have an impact on medico-surgical outcome for liver and kidney transplantations.