Latest database descriptions

Objectives of the Lower Normandy Specialist Regional Registry for Hematology in terms of public health (surveillance, evaluation)

1) Descriptive epidemiology and temporal and spatial monitoring of all hematological malignancies in Lower Normandy: Hodgkin's lymphoma, non-Hodgkin's malignant lymphoma, acute and chronic leukemia including chronic lymphocytic leukemia, multiple myeloma of the bones, myelodysplastic and myeloproliferative syndromes.

2) Study of the risk factors of hematological malignancies.

In view of the existence in Lower Normandy of nuclear sites in the Nord-Cotentin (AREVA NC La Hague plant, Flamanville plant, ANDRA low- and intermediate-level radioactive waste repository, military arsenal servicing nuclear submarines), extra careful monitoring of hematological malignancies is carried out around these sites by the RRHMBN. Mapping of hematological malignancies is carried out in this context - in both children and adults. This does not only concern leukemia, but also all hematological malignancies, including lymphoma.

Given the installation of the very high voltage line corridor between the Flamanville plant and Brittany, the RRHMBN has set up a "zero point" field for hematological malignancies in the corresponding zone. This starting point will form a reference for any subsequent research.


3) Evaluation of hematological malignancy treatment in different populations (elderly people, countryside dwellers) in Lower Normandy and study of the care streams and type of treatment depending on age, residential area and type of HM.

This research will be performed jointly by all of the Lower Normandy registries brought together under a Federation as well as by the FRANCIM network, associating all accredited registries.

To evaluate the risk of cardiovascular disease (cerebrovascular accident, myocardial infarction and pulmonary embolism) in connection with hormone therapy for menopause while considering the administration route for oestrogen and types of progestin.

- Carry out a descriptive epidemiological analysis of the population suffering from Gaucher's disease in France (prevalence estimated at 1/100,000) which makes it possible to describe the natural history of the disease, apprehend and analyze the care practices, and evaluate them.
- Develop lines of research:
* Epidemiology and modeling of the change in biological and clinical markers with and without treatment
* Pregnancy and Gaucher's disease
* Parkinson's disease and Gaucher's disease
* Monoclonal peak and Gaucher's disease
* Type-3 Gaucher's disease
* Gaucher's disease in children
- Evaluate the efficacy and the tolerance of the treatments, optimize them and carry out pharmacoeconomic studies
- Establish any genotype-phenotype relations
- Detect predictive factors of complications and identify the biomarkers making it possible to follow the disease with and without treatment
- Select the patients for new therapeutic options

PMSI is a tool for medico-economic analysis of hospital activity. Its main purpose is to describe hospital activity to enable a better division of budgetary envelopes, according to the medical and economic complexity of the pathologies treated in each establishment. By its medical-administrative content, it allows to study hospital morbidity and its caring (diagnosis and actions), and the analysis of regional and interregional fluxes of hospitalizations. It's finally used as an internal management tool for some health establishments.

A collection of synthetic medical information respecting a normalized format has been created for hospitalizations into structures having an authorized activity in follow-up and rehabilitation care. The object of this collection and its treatment is to allow a quantified description, in medical terms, of the activity of the establishment and, on the other hand, through an algorithm based on the information contained in the collection, to group the hospital stays in defined sets, which could found a part of the financing of the establishments.

The collection concerns every kind of hospital stay, complete or partial, in public or private establishments. The collect rules are regularly established. For public or private establishments participating to hospital public service, the collect began the 1st July 1998, and for other private establishments from 1st July 2003. The specificities of the PMSI-SSR (FRC) collect are the following: - recaps are constituted per calendar week, from Monday to Sunday. A FRC hospital stay is covered by one pr more standardizes weekly recaps (SWR, RHS in French). - Three professional categories participate to the collect: doctors (diagnosis and medical actions), nurses (dependence score/Everyday activities grid), reeducators (rehabilitation and readaptation acts)