EVALHOSPITAM OR EVHAN - Evaluation of hospitalisation for patients with anorexia nervosa: Efficacy of treatment and research predictive outcome factors 
Head :
Godart Nathalie, U669 INSERM TROUBLES DES CONDUITES DE L'ADOLESCENT
Last update : 03/01/2020 | Version : 2 | ID : 60159
| General | |
| Identification | |
| Detailed name | Evaluation of hospitalisation for patients with anorexia nervosa: Efficacy of treatment and research predictive outcome factors |
| Sign or acronym | EVALHOSPITAM OR EVHAN |
| CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | CNIL : 25/09/2009 |
| General Aspects | |
| Medical area |
Psychology and psychiatry |
| Health determinants |
Addictions Nutrition Social and psychosocial factors |
| Keywords | clinical outcome, Morgan and Russell scale, body mass index, menstruation, somatic complications, psychiatric complications, social adjustment, treatment received, Health episodes, mortality |
| Scientific investigator(s) (Contact) | |
| Name of the director | Godart |
| Surname | Nathalie |
| Address | 75014 PARIS |
| Phone | + 33 (0)1 56 61 69 35 |
| nathalie.godart@imm.fr | |
| Unit | U669 INSERM TROUBLES DES CONDUITES DE L'ADOLESCENT |
| Organization | INSERM - Institut National de Santé et Recherche |
| Collaborations | |
| Funding | |
| Funding status |
Mixed |
| Details | Contrat d'interface INSERM, PHRC 2006, ANR JEUNE CHERCHEUR 2007, CNAM, contrat CIFRE, bourse EIFFEL, fondation de France |
| Governance of the database | |
| Sponsor(s) or organisation(s) responsible | INSTITUT MUTUALISTE MONSOURIS |
| Organisation status |
Public |
| Additional contact | |
| Main features | |
| Type of database | |
| Type of database |
Study databases |
| Study databases (details) |
Longitudinal study (except cohorts) |
| Database recruitment is carried out by an intermediary |
A selection of health institutions and services |
| Database recruitment is carried out as part of an interventional study |
No |
| Additional information regarding sample selection. | Prospective Other bodies active in creating this cohort: CHU AND CHG and research laboratory. Closing date for inclusion: 01/03/2010 |
| Database objective | |
| Main objective | General objective: to evaluate the impact (efficacy) of five different inpatient treatment modalities for anorexia nervosa. Individual global health outcome (physical, psychiatric, nutritional and social) will be measured on a short-term basis (on discharge), as well as hospital treatment meeting or exceeding statutory charges on a medium term basis (12 months), taking into account confounding factors and recognised prognostic factors. Global health is evaluated using the Morgan and Russell scale as well as secondary criteria for deteriorating health (see evaluation criteria methodology). Secondary objectives: - to determine predictive factors for failures in inpatient treatment, duration of hospitalisation, and treatment costs using clinical epidemiology methodology. - to begin a long-term prospective study to evaluate the psychological, physical, nutritional and social outcome of a homogeneous cohort of subjects suffering from severe anorexia nervosa. - two "ancillary" biological sub-projects: - to evaluate the development of depressive and anxiety symptoms in relation to changes in clinical nutritional status and serotonin markers - to evaluate cellular immunity development in relation to changes in clinical nutrition. |
| Inclusion criteria | - Patients between 8 and 65 years old; - patients hospitalised for anorexia nervosa (who only receive treatment by necessity of somatic condition: rapid weight loss, or significantly underweight with a BMI of less than 15, or their psychological condition), as well as parents of minor and adult patients still living at home; - obtained written consent; - patients not covered by social security health insurance. |
| Population type | |
| Age |
Childhood (6 to 13 years) Adolescence (13 to 18 years) Adulthood (19 to 24 years) Adulthood (25 to 44 years) Adulthood (45 to 64 years) |
| Population covered |
Sick population |
| Gender |
Male Woman |
| Geography area |
National |
| Detail of the geography area | Multicentric cohort throughout France (11 centres): Île-de-France: 6 centres, Bordeaux: 2 centres, Nantes: 1 centre, Rouen: 1 centre, Saint-Étienne: 1 centre. |
| Data collection | |
| Dates | |
| Date of first collection (YYYY or MM/YYYY) | 03/2009 |
| Date of last collection (YYYY or MM/YYYY) | 03/2010 |
| Size of the database | |
| Size of the database (number of individuals) |
< 500 individuals |
| Details of the number of individuals | 180 |
| Data | |
| Database activity |
Data collection completed |
| Type of data collected |
Declarative data Biological data |
| Declarative data (detail) |
Face to face interview |
| Biological data (detail) | Type of samples collected: all analysis during hospitalisation (standard protocol), serotonin, tryptophan, CD4/CD8. |
| Presence of a biobank |
No |
| Health parameters studied |
Health event/morbidity Health event/mortality |
| Procedures | |
| Data collection method | Self-administered questionnaire: direct input Interview: direct input Clinical examinations: direct input Biological analysis: direct input |
| Participant monitoring |
Yes |
| Details on monitoring of participants | (Indefinite duration) |
| Links to administrative sources |
Yes |
| Linked administrative sources (detail) | CépiDc |
| Promotion and access | |
| Promotion | |
| Link to the document | http://tinyurl.com/Hal-EVALHOSPITAM-EVHAN |
| Description | Liste des publications dans HAL |
| Link to the document | http://www.ncbi.nlm.nih.gov/pubmed/?term=EVALHOSPITAM+OR+EVHAN+OR+22378228[uid] |
| Description | Liste des publications dans Pubmed |
| Access | |
| Terms of data access (charter for data provision, format of data, availability delay) | To be decided if data may be used by academic teams. Data may not be used by industrial teams. |
| Access to aggregated data |
Access on specific project only |
| Access to individual data |
Access on specific project only |
