Latest database descriptions

Cohort of children with chromosomal structure abnormality

April 09 2015

The main objective of this cohort is clinical 1) Acquire information about motor, cognitive and physical development of patients carriers of micro-reorganizations depending on the type of anomaly declared 2) Define, through a longitudinal follow-up, the morbid complications (neurological progress or degradation, epilepsy, incidence of common pathologies) and mortality rate of these patients 3) Specify psychological, medical and social caring parameters, education and socialization of these patients, medico-economic consequences.
Secondary objective : Introduce, at the level of French population, the overall impact, the distribution by type of abnormality and by chromosomal region, the effects of environment variables such as parents age,...

Multicentric cohort of patients with compensated and non-complicated alcoholic cirrhosis, designed to study the incidence and predictors of hepatocellular carcinoma (HCC)

August 07 2019

General objective: to describe the natural history of hepatocellular carcinoma (HCC) in alcoholic cirrhosis. Secondary objectives: - to establish a comparison with the national cohort - to establish a comparison with the national cohort of viral cirrhosis ANRS CO12 CirVir - to form an ancillary study database from biological resources taken at enrolment and afterwards annually as well as associated clinical data.

Contraception and recurrent venous event

April 09 2015

General objective: to study whether or not different forms of hormonal contraception contribute to the risk of venous thrombosis recurrence for women at high risk of venous thromboembolism.

From Uncomplicated Alcoholism to Korsakoff's Syndrome: Clinical, Genetic, Neuropsychological and Brain Examinations

April 09 2015

To specify the physiopathological processes resulting in alcohol-related brain abnormalities and neuropsychological disorders. To identify the factors explaining the heterogeneity of alcohol-related brain abnormalities and neuropsychological disorders. To investigate the neural substrates of Theory of Mind deficits in alcohol dependent patients with no neurological complications. To examine the brain mechanisms underlying neuropsychological recovery in AL patients with abstinence.

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