Latest database descriptions

Description of the natural history of HBV and/or HCV compensated cirrhosis.

General objective: To evaluate the medium and long-term clinical impact of therapeutic strategies with the help of marginal structural models. Secondary objectives - to assess non-AIDS-defining morbidity and mortality and the impact of HIV infection and/or treatment for cancer as well as vascular and metabolic diseases. - to contribute to epidemiological monitoring of HIV infection in France (descriptive epidemiology and establishment of model). - to participate in international collaborations on treated patient prognosis as well as morbidity and mortality in previously diagnosed individuals.

To study the etiopathogenesis of psychiatric disorders in the elderly by identifying associated risk factors throughout life in elderly people with previous psychiatric history. - to identify depressive symptom subtypes regardless of current nosology; - to describe age-related changes in stress reactivity; - to assess the validity of current gene interaction/stress models for depression described in young subjects for elderly subjects; - to evaluate the usefulness of complete genome exploration based on haplotypes as well as a pilot study of clinical pools based on symptom severity; - to find the most relevant etiological models derived from multiple risk factors and interaction to explain the onset of illness and symptom severity; - to suggest future intervention and prevention strategies based on these models.

Establish the causal nature of the link between antioxidant nutrients and risk of cancer, ischemic heart diseases or mortality. Better know the relations between nutrition and health, creating a large data bank on French people food consumption and health condition.