Latest database descriptions

The main objective of the project is to describe geographical disparities of the coronary risk, to examinate if environment characteristics (socio-demographic factors, physical environment, equipment, services and social interaction environment) are associated to the coronary disease and its risk factors, and to identify the mechanism at work taking into account experiences in the neighbourhoodk, knowledge/beliefs and people's health behaviours.
Secondary objective : generally , Record cohort will allow to study in a comprehensive manner the existing relations between geographic life environment and several health variables (mental health, dental health, health care use).

General objective: To identify new biomarkers along with environmental and genetic risk factors for chronic kidney disease progression and related complications Secondary objectives: - To describe the natural history of chronic kidney disease in terms of optimised treatment according to international recommendations - To evaluate the realisation and relevance of the recommended objectives (K/DOQI, KDIGO, HAS)

Study brain and functional ageing after 65 years old, distinguish normal and pathological modalities, and identify physical or intellectual deterioration high-risk individuals, in order to plan a preventive action.

General objective: to form a cohort of BRCA gene mutation carriers for standardised data collection and to establish a prospective follow-up over 10 years. Treatment for families can be improved by resolving certain questions (projects with associated INSERM teams): 1) what is the risk of developing breast and/or ovarian cancer for gene mutation carriers during their lifetime? 2) are cancer risks modified by environmental factors (in particular medical radiation), hormonal factors (endogenous or exogenous), or other genetic factors? 3) should the same parameters be used to evaluate the prognosis of sporadic cancer? 4) what is the psychological and social impact for people with a known predisposition to breast and/or ovarian cancer?