Latest database descriptions

From an epidemiological standpoint:
1) Determination of frequency (in terms of prevalence) and distribution of congenital malformation;
2) Identification of the risk factors of malformations (discomfort, environment, medications and toxic)
3) Determination of malformation ""clusters"" for decision aids in the event of a significant increase in the prevalence of a malformation type (monitoring-alert);
4) Making data available for epidemiological studies
From a public health standpoint
1) Assessment of the impact of health policies in the field of perinatal medicine and the impact of regional obstetric practices;
2) Measuring the effectiveness of the prevention and establishment of support to inform healthcare professionals, especially in the field of teratology;
3) Assessment of healthcare requirements in perinatal medicine (birthing methods and locations);
From a clinical standpoint:
1) Locating new malformation associations and even the identification of new symptoms;
2) Determination of modes of genetic disorder transmission;
3) Establishment of interactions among various active partners in prevention, socio-educational care in the region concerned.

To study the correlations between phenotypic peculiarities in patients (onset of IBD, disease progression, treatment response), ASCA and ANCA serological markers and allelic status of NOD2/CARD15 gene.

Secondary objectives:
- to analyse therapeutic management and surgical predictors for each UC and CD group;
- to investigate the development of paediatric forms in adulthood in terms of growth (Z score) and socio-professional level (level of education, age and category of last diploma, current profession);
- to establish a database to evaluate the impact of other genetic polymorphisms in order to investigate possible epistasis of these polymorphisms with CARD15/NOD2.

Know the incidence and prevalence of IBDs in a geographical zone representing 10% of the French population. Construct analytical epidemiological study for physiopathogenetic factors behind IBDs

The survey's primary objectives are to describe and analyse the work situations of active workers and their trends; to link up different work components; to observe technology trends and its impact on work and to describe occupational risks and prevention practices.