Latest database descriptions

Describe and compare the socio-demographic characteristics of patients infected with an HIV-1 of subtype B (group 1) compared to non-B (group 2) treated with a first anti-retroviral drug treatment.
Compare according to the HIV subtype the stage of the disease (clinical, viro-immunology, co-morbidities) at the time treatment is initiated, compare between the 2 groups (B and non-B) the conditions for taking the treatment and the perception by the patient of the therapy and of its effects.
Identification of any correlation between these latter parameters and the change in the disease between the initiation and the first line ARV and the inclusion in the cohort:
- change in the viral load (VL) according to the ARV treatment (PI, NNRTI) and of the HIV subtype (B or non-B), of the CD4,
- any occurrence of clinical events,
- any changes in treatments and reasons.

To estimate the prevalence of Fabry disease in a population of men and women with hypertrophic cardiomyopathy (HCM) consistent with primary cardiomyopathy.

Study parents' knowledge and practices and their determinants in managing fever symptoms in children in France as compared with current recommendations.

The permanent monitoring of the Bas-Rhin population aged 35 to 74 and systematic, continuous recording of cases of myocardial infarction and coronary deaths allow for the continuous estimation - as well as development - of a certain number of epidemiological indicators concerning coronary disease: incidence rates, annual occurrence rates (incident and recurring events), death rates by myocardial infarction; coronary and presumed coronary death rates; fatality rate at 28 days - hospital and general coronary. These indicators can be supplied by gender, age and year.
Although changes in trend are observed over time, it is possible to estimate the proportion attributable to the reduction in incidence of coronary events and the proportion attributable to the reduction in fatality.
Joint analyses are performed on a regular basis with the other two French registries on ischaemic heart diseases, which use the same methodology.
The register is a reference tool for validating epidemiological indicators for coronary disease, constructed from other data sources (estimation validation of indicators from the PMSI hospital database for myocardial infarction, validation of indicators for coronary mortality and sudden death from the CépiDc's national death statistics).

Parallel to recording coronary disease, surveys on representative samples of the general population are carried out at regular intervals with a view to studying the level of cardiovascular risk factors and how they evolve.

Development of descriptive studies completing the basic recording: since 2006, recording of all acute heart failure (myocardial infarction, acute coronary syndromes, unstable angina); periodic recording of out- and inpatient treatment for episodes of acute heart failure, etc.

Thanks to the ischaemic heart disease register, several analytical epidemiology studies have been developed (ECTIM case-control and PRIME cohort). Use of data from the register to evaluate the merits of an approach measuring - on an ecological basis - the influence of lifestyle and socioeconomic status on the link between atmospheric pollution and myocardial infarction in the Urban Community of Strasbourg (CUS).