Latest database descriptions

Primary objective: evaluate 1-month mortality (at 28 days and 31 days) of patients treated with drotrecogin alpha (activated) in intensive care forsevere sepsis and describe causes of death.
Secondary objectives: characteristics of patients and conditions of use.

To describe utilisation of newly prescribed statins in French primary care

General objective: study the relations between global eating behaviors and/or some specific nutritional factors (provisions and status of anti-oxydants, folates, Omega 3 PUFA, energetic and protein provision, etc.) evaluated from data collected between 1994 and 1996 on a large population of mature adults, and:
- The global quality of ageing among this population, evaluated 12 and 15 years later (2006 and 2009) through a global indicator, realized from different components determining successful aging (cognitive state, mood, nutritional status, bone status, balance disorders, sensory disorders, perceived health, integration, social, physical activity, pathologies existence).
- Each specific different specific functional component related to the quality of aging: cognitive functions and depression, risk of sarcopenias or osteoporosis, insulin resistance, life quality, chronic diseases (cancers, cataract, macular degeneration). Secondary objective: evaluate the role of oxidative stress, inflammatory status, insulin resistance, some genetic factors implied in the relation between nutritional behaviors, and/or some more specific nutritional factors, and aging quality

General objective: To investigate determinants for long-term effects of adherence and tolerance to highly active antiretroviral drugs, in relation to patients infected with HIV-1 who were treated for the first time under a protease inhibitor in 1997-99. Secondary objectives: - to determine the part that host genetic polymorphisms play in the progression of the infection and onset of serious adverse events - to investigate viral load and antiretroviral resistance in plasma cell compartments in relation to antiretroviral concentrations over time.