Last update : 07/07/2015 | Version : 2 | ID : 60145
General | |
Identification | |
Detailed name | Study of Cancer Incidence and Mortality Among Agricultural Workers in France |
Sign or acronym | AGRICAN |
CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | Accord CNIL : 02/08/2005 |
General Aspects | |
Medical area |
Cancer research |
Health determinants |
Nutrition Occupation Social and psychosocial factors |
Keywords | Mortality, rural population, incidence, localisation |
Scientific investigator(s) (Contact) | |
Name of the director | Lebailly |
Surname | Pierre |
Address | 14076 CAEN |
Phone | +33 (0)2 31 45 51 23 |
p.lebailly@baclesse.fr | |
Unit | GRECAN |
Organization | Centre François |
Collaborations | |
Participation in projects, networks and consortia |
Yes |
Funding | |
Funding status |
Mixed |
Details | Agence française de sécurité sanitaire de l'environnement et du travail, Institut National sur le CAncer, Mutualité Sociale Agricole, Fondation de France, Ligue Nationale de lutte contre le Cancer, Association pour la recherche sur le cancer, Union des industries de la protection des plantes |
Governance of the database | |
Sponsor(s) or organisation(s) responsible | CENTRE RÉGIONAL DE LUTTE CONTRE LE CANCER FRANÇOIS BACLESSE |
Organisation status |
Public |
Additional contact | |
Main features | |
Type of database | |
Type of database |
Study databases |
Study databases (details) |
Cohort study |
Database recruitment is carried out by an intermediary |
A population file |
Database recruitment is carried out as part of an interventional study |
No |
Additional information regarding sample selection. | Prospective Inclusion cut-off date: 01/12/2007 Other bodies active in creating this cohort: MSA 188,000 included from 565,000 contacts |
Database objective | |
Main objective | General objective: To study cancer risk associated with agricultural occupational exposure according to cancer type Secondary objective: to determine the risk of cancer in the rural population |
Inclusion criteria | Adults affiliated with specialised health insurance (MSA) for at least 4 years Residing in one of the concerned 12 départements at the time of enrolment |
Population type | |
Age |
Adulthood (19 to 24 years) Adulthood (25 to 44 years) Adulthood (45 to 64 years) Elderly (65 to 79 years) Great age (80 years and more) |
Population covered |
General population |
Gender |
Male Woman |
Geography area |
National |
Detail of the geography area | Multicentric cohort throughout France (12 centres). Geographical area covered: 12 Départments: Calvados, Côte d'Or, Doubs, Gironde, Isère, Loire Atlantique, Manche, Bas Rhin, Haut Rhin, Somme, Tarn, Vendée |
Data collection | |
Dates | |
Date of first collection (YYYY or MM/YYYY) | 11/2005 |
Size of the database | |
Size of the database (number of individuals) |
Greater than 20 000 individuals |
Details of the number of individuals | 188 000 |
Data | |
Database activity |
Data collection completed |
Type of data collected |
Declarative data Biological data |
Declarative data (detail) |
Paper self-questionnaire |
Biological data (detail) | Type of samples taken: blood and urine from 800 individuals |
Presence of a biobank |
Yes |
Contents of biobank |
Serum Fluids (saliva, urine, amniotic fluid, …) DNA Others |
Details of biobank content | Serum bank, DNA bank, lymphocytes, urine |
Health parameters studied |
Health event/morbidity Health event/mortality |
Procedures | |
Data collection method | Self-administered questionnaire from a paper questionnaire (optical input) Biological analysis: handwritten with double input |
Participant monitoring |
Yes |
Details on monitoring of participants | Follow-up duration: 10 years |
Links to administrative sources |
Yes |
Linked administrative sources (detail) | Databases used: CépiDc, other health insurance databases, pathology registry |
Promotion and access | |
Promotion | |
Link to the document | http://www.ncbi.nlm.nih.gov/pubmed?term=agrican&cmd=correctspelling |
Description | List of publications in Pubmed |
Access | |
Terms of data access (charter for data provision, format of data, availability delay) | Data may be used by academic teams Data may be used by industrial teams. Access: on submission of project to steering committee according to modalities outlined in the cohort operation charter |
Access to aggregated data |
Access on specific project only |
Access to individual data |
Access on specific project only |
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