AGRICAN - Study of Cancer Incidence and Mortality Among Agricultural Workers in France

Head :
Lebailly Pierre, GRECAN

Last update : 07/07/2015 | Version : 2 | ID : 60145

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Métadonnées
Identification
General Aspects
Scientific investigator(s) (Contact)
Collaborations
Funding
Governance of the database
Additional contact
Type of database
Database objective
Population type
Dates
Size of the database
Data
Procedures
Promotion
Access
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General
Identification
Detailed name Study of Cancer Incidence and Mortality Among Agricultural Workers in France
Sign or acronym AGRICAN
CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation Accord CNIL : 02/08/2005
General Aspects
Medical area Cancer research
Health determinants Nutrition
Occupation
Social and psychosocial factors
Keywords Mortality, rural population, incidence, localisation
Scientific investigator(s) (Contact)
Name of the director Lebailly
Surname Pierre
Address 14076 CAEN
Phone +33 (0)2 31 45 51 23
Email p.lebailly@baclesse.fr
Unit GRECAN
Organization Centre François
Collaborations
Participation in projects, networks and consortia Yes
Funding
Funding status Mixed
Details Agence française de sécurité sanitaire de l'environnement et du travail, Institut National sur le CAncer, Mutualité Sociale Agricole, Fondation de France, Ligue Nationale de lutte contre le Cancer, Association pour la recherche sur le cancer, Union des industries de la protection des plantes
Governance of the database
Sponsor(s) or organisation(s) responsible CENTRE RÉGIONAL DE LUTTE CONTRE LE CANCER FRANÇOIS BACLESSE
Organisation status Public
Additional contact
Main features
Type of database
Type of database Study databases
Study databases (details) Cohort study
Database recruitment is carried out by an intermediary A population file
Database recruitment is carried out as part of an interventional study No
Additional information regarding sample selection. Prospective Inclusion cut-off date: 01/12/2007 Other bodies active in creating this cohort: MSA 188,000 included from 565,000 contacts
Database objective
Main objective General objective: To study cancer risk associated with agricultural occupational exposure according to cancer type Secondary objective: to determine the risk of cancer in the rural population
Inclusion criteria Adults affiliated with specialised health insurance (MSA) for at least 4 years Residing in one of the concerned 12 départements at the time of enrolment
Population type
Age Adulthood (19 to 24 years)
Adulthood (25 to 44 years)
Adulthood (45 to 64 years)
Elderly (65 to 79 years)
Great age (80 years and more)
Population covered General population
Gender Male
Woman
Geography area National
Detail of the geography area Multicentric cohort throughout France (12 centres). Geographical area covered: 12 Départments: Calvados, Côte d'Or, Doubs, Gironde, Isère, Loire Atlantique, Manche, Bas Rhin, Haut Rhin, Somme, Tarn, Vendée
Data collection
Dates
Date of first collection (YYYY or MM/YYYY) 11/2005
Size of the database
Size of the database (number of individuals) Greater than 20 000 individuals
Details of the number of individuals 188 000
Data
Database activity Data collection completed
Type of data collected Declarative data
Biological data
Declarative data (detail) Paper self-questionnaire
Biological data (detail) Type of samples taken: blood and urine from 800 individuals
Presence of a biobank Yes
Contents of biobank Serum
Fluids (saliva, urine, amniotic fluid, …)
DNA
Others
Details of biobank content Serum bank, DNA bank, lymphocytes, urine
Health parameters studied Health event/morbidity
Health event/mortality
Procedures
Data collection method Self-administered questionnaire from a paper questionnaire (optical input) Biological analysis: handwritten with double input
Participant monitoring Yes
Details on monitoring of participants Follow-up duration: 10 years
Links to administrative sources Yes
Linked administrative sources (detail) Databases used: CépiDc, other health insurance databases, pathology registry
Promotion and access
Promotion
Link to the document http://www.ncbi.nlm.nih.gov/pubmed?term=agrican&cmd=correctspelling
Description List of publications in Pubmed
Access
Terms of data access (charter for data provision, format of data, availability delay) Data may be used by academic teams Data may be used by industrial teams. Access: on submission of project to steering committee according to modalities outlined in the cohort operation charter
Access to aggregated data Access on specific project only
Access to individual data Access on specific project only

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