Last update : 09/05/2017 | Version : 1 | ID : 121
General | |
Identification | |
Detailed name | Long term observational study on the therapeutic management of knee osteoarthritis by general practitioners |
Sign or acronym | ATLANTIS |
CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | CNIL n°903352 (22/11/2003) |
General Aspects | |
Medical area |
Rheumatology |
Others (details) | gonarthrosis, Arthrosis |
Keywords | therapeutic management, paracetamol, patient reported outcomes |
Scientific investigator(s) (Contact) | |
Name of the director | Payen-Champenois |
Surname | Catherine |
Address | 3, rue J. Monnier - 92500 Rueil Malmaison |
Phone | +33 (0)1 58 83 60 00 |
catherine.payen-champenois@bms.com | |
Unit | Bristol-Myers Squibb |
Name of the director | Schmidely |
Surname | Nathalie |
Address | 3, rue J. Monnier - 92500 Rueil Malmaison |
Phone | +33 (0)1 58 83 60 00 |
nathalie.schmidely@bms.com | |
Unit | Bristol-Myers Squibb |
Collaborations | |
Funding | |
Funding status |
Private |
Details | Bristol-Myers Squibb |
Governance of the database | |
Sponsor(s) or organisation(s) responsible | Bristol-Myers Squibb (BMS) |
Organisation status |
Private |
Additional contact | |
Main features | |
Type of database | |
Type of database |
Study databases |
Study databases (details) |
Cohort study |
Database recruitment is carried out by an intermediary |
A selection of health care professionals |
Database recruitment is carried out as part of an interventional study |
No |
Additional information regarding sample selection. | Random sampling in clusters |
Database objective | |
Main objective |
Evaluate, in general practice, the change in the first-line therapeutic strategy in patients suffering from knee osteoarthritis, over one year, specially: - Evaluate the percentage of patients treated with each therapeutic modality at the end of the one year observation period. - Describe the modifications implemented in the therapeutic management and identify the reasons justifying these modifications. |
Inclusion criteria |
1. Males or females 50 years or older suffering from symptomatic osteoarthritis of the knee 2. Not treated over the last 6 months for this pathology (non-pharmaceutical treatments and self-medication by analgesics or NSAIDs at low doses will be allowed). 3. For whom the physician will have decided to initiate a first-line treatment in line with the recommendations of EULAR 2000-2003 (paracetamol - systematically taken at a dose of 3 to 4g/d - as pharmacological monotherapy in combination with non-pharmaceutical treatments). |
Population type | |
Age |
Adulthood (19 to 24 years) Adulthood (25 to 44 years) Adulthood (45 to 64 years) Elderly (65 to 79 years) Great age (80 years and more) |
Population covered |
Sick population |
Gender |
Male Woman |
Geography area |
International |
Detail of the geography area | France and Spain |
Data collection | |
Dates | |
Date of first collection (YYYY or MM/YYYY) | 2003 |
Date of last collection (YYYY or MM/YYYY) | 2006 |
Size of the database | |
Size of the database (number of individuals) |
[1000-10 000[ individuals |
Details of the number of individuals | 1114 (586 in France, 528 in Spain) |
Data | |
Database activity |
Data collection completed |
Type of data collected |
Clinical data Declarative data |
Clinical data (detail) |
Direct physical measures Medical registration |
Declarative data (detail) |
Face to face interview |
Presence of a biobank |
No |
Health parameters studied |
Health care consumption and services Quality of life/health perception |
Care consumption (detail) |
Hospitalization Medical/paramedical consultation Medicines consumption |
Procedures | |
Data collection method | paper case report form |
Participant monitoring |
Yes |
Details on monitoring of participants | M3, M6, M9, M12 |
Links to administrative sources |
No |
Promotion and access | |
Promotion | |
Access | |
Terms of data access (charter for data provision, format of data, availability delay) | Publications |
Access to aggregated data |
Access on specific project only |
Access to individual data |
Access on specific project only |
Partners - FAQ - Contact - Site map - Legal notices - Administration - Updated on December 15 2020 - Version 4.10.05