D.E.S.IR. - Epidemiological data about insulin resistance syndrome

Head :
Balkau Beverley, U1018 Centre de Recherche en Epidémiologie et santé des Populations (CESP)

Last update : 05/07/2015 | Version : 3 | ID : 3520

print
Print
xml
XML

Export to XML

Please choose the format :

pdf
PDF
xml
CSV (Excel)

Export to CSV

What sections do you want to export ?

Métadonnées
Identification
General Aspects
Collaborations
Funding
Governance of the database
Scientific investigator(s) (Contact)
Additional contact
Type of database
Database objective
Population type
Dates
Size of the database
Data
Procedures
Promotion
Access
Select all | Invert selection | No selection

Which version do you want to export ?

send
Send
General
Identification
Detailed name Epidemiological data about insulin resistance syndrome
Sign or acronym D.E.S.IR.
CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation Date de réception de l'avis favorable de la CNIL : 27/05/1994
General Aspects
Medical area Cardiology
Endocrinology and metabolism
Health determinants Genetic
Nutrition
Keywords insulin resistance syndrome, Incidence, diabetes, hypertension, dyslipidemia, cardiovascular diseases
Collaborations
Participation in projects, networks and consortia Yes
Details Involvement in a cohort network: DETECT-2 study, to study diabetes diagnosis criteria
Others Other related cohorts: cameroun cohort, multiple cohorts
Funding
Funding status Mixed
Details Contrat Inserm-Cnamts, Inserm - réseaux en santé publique, Inserm -interactions entre les déterminants de santé, les centres d'examens de santé Cornes, TGIR 2009-2010, Novartis pharma, sanofi aventis, Association Diabète Risque vasculaire, Fédération Française de Cardiologie, La Fondation de France, Alfediam, Anivins, Ardix médical, Bayer Diagnostics, Becton Dickinson, Cardionics, Lilly France, Merck Santé, Novo Nordisk, Pierre Fabre, Roche, Topcon
Governance of the database
Sponsor(s) or organisation(s) responsible INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM
Organisation status Public
Scientific investigator(s) (Contact)
Name of the director Balkau
Surname Beverley
Address Hôpital Paul Brousse -16 av Paul Vaillant Couturier -94807 VILLEJUIF
Phone +33 (0)1 45 59 51 61
Email beverley.balkau@inserm.fr
Unit U1018 Centre de Recherche en Epidémiologie et santé des Populations (CESP)
Organization INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE -
Additional contact
Main features
Type of database
Type of database Study databases
Study databases (details) Longitudinal study (except cohorts)
Database recruitment is carried out as part of an interventional study No
Additional information regarding sample selection. Individuals inclusion mode: perspective. End of inclusions: 01/02/1996. Sample of patients consulting into Health Examination Centers
Database objective
Main objective Describe natural history of insulin resistance syndrome and its consequences.
Evaluate diabetes risk factors.
Inclusion criteria Men and women, aged between 30 and 65, consulting in the examination centers
Population type
Age Adulthood (25 to 44 years)
Adulthood (45 to 64 years)
Population covered Sick population
Gender Male
Woman
Geography area Regional
French regions covered by the database Centre-Val de Loire
Pays de la Loire
Detail of the geography area Loire valley area
Data collection
Dates
Date of first collection (YYYY or MM/YYYY) 06/1994
Date of last collection (YYYY or MM/YYYY) 2010
Size of the database
Size of the database (number of individuals) [1000-10 000[ individuals
Details of the number of individuals 5212
Data
Database activity Data collection completed
Type of data collected Clinical data
Declarative data
Paraclinical data
Biological data
Administrative data
Clinical data (detail) Medical registration
Details of collected clinical data Clinical examination at inclusion and during the follow-up. Examination frequency : 3 years. Information collected during clinical examination: blood pressure, weight, waist size, height, ECG, ankle/brachial index
Declarative data (detail) Face to face interview
Details of collected declarative data Clinical examination at inclusion and during the follow-up. Examination frequency : 3 years. Information collected during clinical examination: blood pressure, weight, waist size, height, ECG, ankle/brachial index
Paraclinical data (detail) Blood pressure, ankle/brachial index, ECG, IMC, waist size, hip circumference
Biological data (detail) Glucidic (glycemia, HbA1c, insulin) and lipid profile, transaminases, creatinine, fibrogen
Administrative data (detail) Age, gender, birthplace
Presence of a biobank Yes
Contents of biobank Serum
Plasma
Fluids (saliva, urine, amniotic fluid, …)
DNA
Details of biobank content On an empty stomach: plasma, serum, DNA, urine
Health parameters studied Health event/morbidity
Health event/mortality
Procedures
Data collection method The main clinical data are collected at inclusion, then every 3 years during the follow-up (blood pressure, weight, waist circumference, size, electrocardiography (ECG), ankle-brachial pressure index). During the follow-up, the family doctor fills a questionnaire in case of a cardiovascular event. Declarative data are collected through a self-questionnaire (medicine, diet, tobacco addiction, lifestyle, diseases) at inclusion, then every year. A questionnaire has been proposed by interview (diseases, family history) at inclusion and every 3 years. Year of last data collection: 2004, examination for the participants, 2010 for death causes. Self-questionnaires: manual data entry Interviews: manual data entry Clinical examination: manual data entry Biological examination: direct data entry
Quality procedure(s) used Coherence request during and after computer data entry. Missing data checked back to the original file and/or to a third. Subjects remainders for follow-up visits. Patients receive information about the use of their data.
Participant monitoring Yes
Details on monitoring of participants During 9 years
Links to administrative sources Yes
Linked administrative sources (detail) CépiDC, and RNIPP for the follow-up of vital status and medical death causes
Promotion and access
Promotion
Link to the document http://www.hal.inserm.fr/DESIR
Description List of publications in HAL
Link to the document http://www.ncbi.nlm.nih.gov/pubmed/?term=%28DESIR+OR+D.E.S.I.R%29+AND+%28insulin+OR+diabetes%29+NOT+desir[author]
Description List of publications in Pubmed
Access
Terms of data access (charter for data provision, format of data, availability delay) Data utilization possible for academic teams and for industrials.

Project demand - access to data and biobank

Beverley Balkau: beverley.balkau@inserm.fr
Fabienne Rakotozafy: fabienne.rakotozafy@irsa.asso.fr
Access to aggregated data Access on specific project only
Access to individual data Access on specific project only

Partners - FAQ - Contact - Site map - Legal notices - Administration - Updated on August 21 2018 - Version 4.06.03

View Edit Create here