Last update : 09/05/2017 | Version : 1 | ID : 6142
General | |
Identification | |
Detailed name | Environment and Adult Lymphoma Genetics |
Sign or acronym | ENGELA |
CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | CNIL: 998198 |
General Aspects | |
Medical area |
Cancer research Hematology Immunology |
Health determinants |
Genetic |
Others (details) | Lymphoid tumours, haematopoietic tumours, non-Hodgkin's lymphoma, Hodgkin's lymphoma, multiple myeloma, lymphoproliferative syndrome |
Keywords | Incidence, genetics, lymphoma |
Scientific investigator(s) (Contact) | |
Name of the director | Clavel |
Surname | Jacqueline |
Address | 16, Avenue Paul Vaillant-Couturier 94807 VILLEJUIF |
Phone | +33 (0)1 45 59 50 38 |
jacqueline.clavel@inserm.fr | |
Organization | Institut National de la Santé et de la Recherche |
Collaborations | |
Participation in projects, networks and consortia |
Yes |
Funding | |
Funding status |
Mixed |
Details | - Association pour la Recherche contre le Cancer - Fondation de France - AFSSET (Agence française de sécurité sanitaire de l'environnement et du travail) - Dons des employés Faberge |
Governance of the database | |
Sponsor(s) or organisation(s) responsible | Institut National de la Santé et de la Recherche Médicale |
Organisation status |
Public |
Additional contact | |
Main features | |
Type of database | |
Type of database |
Study databases |
Study databases (details) |
Case control study |
Database recruitment is carried out by an intermediary |
A selection of health institutions and services |
Database recruitment is carried out as part of an interventional study |
No |
Additional information regarding sample selection. | Subjects selected: - lymphoid haemopathy cases - case-controls treated in hospitals |
Database objective | |
Main objective | To analyse the relationship between lymphoid malignancies and family history of cancer. |
Inclusion criteria | - Men or women - aged between 18 and 75 years old |
Population type | |
Age |
Adulthood (19 to 24 years) Adulthood (25 to 44 years) Adulthood (45 to 64 years) Elderly (65 to 79 years) |
Population covered |
Sick population |
Gender |
Male Woman |
Geography area |
National |
Detail of the geography area | France (Hospitals in Bordeaux, Brest, Caen, Nantes, Lille and Toulouse) |
Data collection | |
Dates | |
Date of first collection (YYYY or MM/YYYY) | 2001 |
Date of last collection (YYYY or MM/YYYY) | 2004 |
Size of the database | |
Size of the database (number of individuals) |
[1000-10 000[ individuals |
Details of the number of individuals | 1586: - 828 cas/cases - 758 témoins/controls |
Data | |
Database activity |
Data collection completed |
Type of data collected |
Clinical data Declarative data Paraclinical data |
Clinical data (detail) |
Direct physical measures |
Declarative data (detail) |
Paper self-questionnaire Face to face interview |
Paraclinical data (detail) | Blood sample |
Presence of a biobank |
Yes |
Contents of biobank |
Serum Tissues DNA |
Details of biobank content | Constitutional DNA, tumour tissue |
Health parameters studied |
Health event/morbidity Health event/mortality Health care consumption and services |
Care consumption (detail) |
Hospitalization |
Procedures | |
Participant monitoring |
Yes |
Links to administrative sources |
No |
Promotion and access | |
Promotion | |
Link to the document | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760125/?tool |
Link to the document | http://oem.bmj.com/content/67/10/664.full.pdf+html |
Link to the document | http://journals.lww.com/joem/pages/articleviewer.aspx?year |
Link to the document | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728754/ |
Link to the document | http://link.springer.com/article/10.1007%2Fs10552-008-9182-1 |
Link to the document | http://www.nature.com/leu/journal/v21/n9/full/2404738a.html |
Link to the document | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1853236/ |
Link to the document | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323431/ |
Link to the document | http://epi.grants.cancer.gov/InterLymph/ |
Access | |
Terms of data access (charter for data provision, format of data, availability delay) | To be defined |
Access to aggregated data |
Access on specific project only |
Access to individual data |
Access on specific project only |
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