ITMO public health
Last update : 12/01/2019 | Version : 1 | ID : 60005
| General | |
| Identification | |
| Detailed name | Cohort of Toulouse Conurbation Workers |
| Sign or acronym | "AZF" Santé Cohort |
| CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | CCTIRS (number 03.143), CNIL (number 904129). |
| General Aspects | |
| Medical area |
Otolaryngology or ENT Psychology and psychiatry |
| Study in connection with Covid-19 |
No |
| Health determinants |
Medicine Occupation Social and psychosocial factors |
| Keywords | Major health events observed: symptoms of post-traumatic stress, depressive symptoms, hearing disorders. Main cohort topics: mental health, auditory health, working life. |
| Scientific investigator(s) (Contact) | |
| Name of the director | Buisson |
| Surname | Catherine |
| Address | 94410 saint Maurice |
| Phone | +33 (0)1 41 79 67 00 |
| c.buisson@invs.sante.fr | |
| Unit | DÉPARTEMENT SANTÉ TRAVAIL (DST) |
| Organization | Institut de Veille |
| Name of the director | Diène |
| Surname | Eloi |
| Address | ARS Midi Pyrénées, 10 chemin du raisin, 31050 Toulouse Cedex |
| Phone | +33 (0)5 34 30 26 81 |
| eloi.diene@ars.sante.fr | |
| Unit | Département santé travailInstitut de veille sanitaire94415 Saint Maurice Cedex |
| Organization | InVS |
| Collaborations | |
| Others | Other related cohorts: COSET: the AZF cohort is a procedure test for COSET and CONSTANCES cohorts. |
| Funding | |
| Funding status |
Public |
| Details | Partnership agreement between InVS, CPAM Toulouse (CES) and INSERM. |
| Governance of the database | |
| Sponsor(s) or organisation(s) responsible | Institut de veille sanitaire |
| Organisation status |
Public |
| Additional contact | |
| Main features | |
| Type of database | |
| Type of database |
Study databases |
| Additional information regarding sample selection. | Inclusion method: Prospective. Other bodies active in creating this cohort: - CPAM-TOULOUSE health examination clinics - INSERM U1018 CESP. Closing date for inclusion: 12/2009. All volunteers from the first cross-sectional study were included in the cohort. |
| Database objective | |
| Main objective |
General objectives:
- To investigate the medium-term health effects from the explosion at the AZF plant that occurred in September 2001 in the population of workers; - To test access procedures for medical-administrative data (ERASMUS) for monitoring large prospective cohorts. |
| Inclusion criteria | Working within the Toulouse conurbation and agreeing to participate in the cohort during the cross-sectional study, carried out between September 2002 and April 2003. |
| Population type | |
| Age |
Adulthood (19 to 24 years) Adulthood (25 to 44 years) Adulthood (45 to 64 years) Elderly (65 to 79 years) |
| Population covered |
General population |
| Gender |
Male Woman |
| Geography area |
Local |
| Detail of the geography area | French study. Geographical area covered: workers in the Toulouse conurbation. |
| Data collection | |
| Dates | |
| Date of first collection (YYYY or MM/YYYY) | 05/2003 |
| Date of last collection (YYYY or MM/YYYY) | 12/2009 |
| Size of the database | |
| Size of the database (number of individuals) |
[1000-10 000[ individuals |
| Details of the number of individuals | 3,000 participants. |
| Data | |
| Database activity |
Data collection completed |
| Type of data collected |
Clinical data Declarative data Paraclinical data Biological data Administrative data |
| Clinical data (detail) |
Direct physical measures Medical registration |
| Details of collected clinical data | Clinical and paraclinical examination: at baseline and final cohort assessment. Information collected is that generated during periodic examinations conducted in the primary Health Insurance Fund examination clinics. Psychiatric diagnosis by MINI. |
| Declarative data (detail) |
Paper self-questionnaire Face to face interview |
| Details of collected declarative data | Self-administered questionnaire on occupation and health: at baseline and during annual follow-up. Self-administered questionnaire time span: 1 (year). Information collected by self-administered questionnaire: *health events and occupational events *mental health scales - psychological unease (GHQ) - depressive symptoms (CES-D) - symptoms of post-traumatic stress (IES-R). Psychiatric diagnosis by MINI - questionnaire is conducted face-to-face in a cohort sub-sample. |
| Paraclinical data (detail) | Radiology, pulmonary function tests, audiograms. |
| Biological data (detail) | Biology, biochemistry. |
| Administrative data (detail) | ERASMUS database. |
| Presence of a biobank |
No |
| Health parameters studied |
Health event/morbidity Health care consumption and services Quality of life/health perception |
| Care consumption (detail) |
Medical/paramedical consultation Medicines consumption |
| Procedures | |
| Data collection method | Annual collection. |
| Quality procedure(s) used | Self-administered questionnaire: optical input from a paper questionnaire (automated data reading) from second year of follow-up. Missing data management: systematic search of individuals' addresses where post was returned undelivered. Subject reminder for follow-up visits? Yes. Patients are informed about the use of their data. |
| Participant monitoring |
Yes |
| Details on monitoring of participants | Follow-up duration: 5 years. |
| Links to administrative sources |
Yes |
| Linked administrative sources (detail) | Database(s) used: ERASMUS. |
| Promotion and access | |
| Promotion | |
| Link to the document | http://www.ncbi.nlm.nih.gov/pubmed/19252759 |
| Link to the document | http://www.ncbi.nlm.nih.gov/pubmed/22020864 |
| Link to the document | http://opac.invs.sante.fr/index.php?lvl |
| Access | |
| Terms of data access (charter for data provision, format of data, availability delay) | - Can data be used by academic teams? Yes: access subject to written request according to InVS data access procedure. |
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