Last update : 06/01/2020 | Version : 1 | ID : 8566
General | |
Identification | |
Detailed name | Cohort on the scalable process of post traumatic stress disorders : The involvement of stress regulation systems and the role of allostatic load |
Sign or acronym | PHOENIX |
CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | CNIL n°1095744 (30/08/2005). CPP : PROM 7806-n°05 01 02 (01/02/2005) |
General Aspects | |
Medical area |
Endocrinology and metabolism Psychology and psychiatry |
Pathology (details) | Affective disorder : post traumatic stress disorder Predictive value of biological and clinical stress markers in the development of PTSD |
Keywords | Post traumatic stress disorder, psychiatric co-morbidities, allostatic load, biologic markers, stress regulation systems, clinical research, epidemiological and prospective research, resilience, PTSD, cortisol, cohort |
Scientific investigator(s) (Contact) | |
Name of the director | Chaudieu |
Surname | Isabelle |
Address | Hôpital la Colombière, 39 avenue Charles Flahault, Pavillon 42. 34093 MONTPELLIER cedex 5 |
Phone | + 33 (0)4 99 61 45 78 |
isabelle.chaudieu@inserm.fr | |
Unit | Inserm U1061 |
Organization | INSERM |
Collaborations | |
Participation in projects, networks and consortia |
Yes |
Details | ABC of psychotraumas, Biological & clinic approches |
Funding | |
Funding status |
Public |
Details | PHRC régional 2004 |
Governance of the database | |
Sponsor(s) or organisation(s) responsible | Promoteur/financeur : PHRC régional CHU de Montpellier |
Organisation status |
Public |
Sponsor(s) or organisation(s) responsible | Coordinateur scientifique : Inserm U1061 |
Organisation status |
Public |
Additional contact | |
Main features | |
Type of database | |
Type of database |
Study databases |
Study databases (details) |
Cohort study |
Database recruitment is carried out by an intermediary |
A selection of health institutions and services |
Database recruitment is carried out as part of an interventional study |
No |
Additional information regarding sample selection. |
- Medical and paramedical examinations - Medicines |
Database objective | |
Main objective |
The main goal of the project is to study the psychological consequences of violent trauma and the predictive value of biological and clinical stress markers in the development of PTSD The specific objectives are : 1) To evaluate the allostatic load level and its development over time 2) To evaluate the prevalence of PTSD and other psychiatric co-morbidities (as depression) on subjects who did endure severe events 3) To determine if the allostatic load level is in link with a chronical development of a post traumatic stress disorder |
Inclusion criteria |
-women and men aged 18 to 75 years -person who have experienced a traumatic event during the previous week (0 to 7 days before) -type of events : physical assault, sexual assault, work accident, road accident, natural disaster. |
Population type | |
Age |
Adulthood (19 to 24 years) Adulthood (25 to 44 years) Adulthood (45 to 64 years) Elderly (65 to 79 years) |
Population covered |
General population |
Gender |
Male Woman |
Geography area |
Local |
French regions covered by the database |
Languedoc-Roussillon Midi-Pyrénées |
Detail of the geography area | Montpellier and its surroundings |
Data collection | |
Dates | |
Date of first collection (YYYY or MM/YYYY) | 05/2005 |
Date of last collection (YYYY or MM/YYYY) | 06/2010 |
Size of the database | |
Size of the database (number of individuals) |
< 500 individuals |
Details of the number of individuals | 124 |
Data | |
Database activity |
Data collection completed |
Type of data collected |
Clinical data Declarative data Biological data |
Clinical data (detail) |
Medical registration |
Declarative data (detail) |
Paper self-questionnaire Face to face interview Phone interview |
Biological data (detail) | Biological data at visit 1, 3 and 4 : - Blood samples : cholesterol, HbA1c, albumin, CRP, orosomucoid - Urine samples : cortisol, adrenaline, norepinephrine |
Presence of a biobank |
Yes |
Contents of biobank |
Serum |
Details of biobank content | 1 ml of serum by subject |
Health parameters studied |
Health event/morbidity Health care consumption and services Others |
Care consumption (detail) |
Medical/paramedical consultation Medicines consumption |
Other (detail) | Resilience Predictive biological markers |
Procedures | |
Data collection method | - Resilience - Predictive biological markers |
Classifications used | DSM IV |
Participant monitoring |
Yes |
Details on monitoring of participants | - Visit 1 (day 1) : clinical psychiatric examination, blood and urine samples, psychometric measures , self and administrated-reported scales - Visit 2 (1 month) : self and administrated-reported scales - Visit 3 (4 month) : clinical psychiatric examination, blood and urine samples, psychometric measures, self and administrated-reported scales - Visit 4 (1 year) : clinical psychiatric examination, blood and urine samples, psychometric measures, self and administrated-reported scales |
Links to administrative sources |
No |
Promotion and access | |
Promotion | |
Link to the document | http://www.ncbi.nlm.nih.gov/pubmed/22768152 |
Link to the document | http://www.ncbi.nlm.nih.gov/pubmed/22768152 |
Access | |
Terms of data access (charter for data provision, format of data, availability delay) | contact the scientist-in-charge |
Access to aggregated data |
Access on specific project only |
Access to individual data |
Access on specific project only |
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