ITMO public health
Last update : 07/07/2015 | Version : 2 | ID : 60066
| General | |
| Identification | |
| Detailed name | Characterisation of Age-Related Bone Loss in Men |
| Sign or acronym | MINOS |
| CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | CNIL 1288625 |
| General Aspects | |
| Medical area |
Geriatrics Rheumatology |
| Health determinants |
Genetic Nutrition |
| Keywords | Observed health events, muscle mass, osteoporosis, fractures, clinical risk factors, falls, physical activity |
| Scientific investigator(s) (Contact) | |
| Name of the director | Delmas |
| Surname | Pierre |
| delmas@lyon.inserm.fr | |
| Unit | U831 |
| Organization | INSERM - Institut National de la Santé et de la Recherche |
| Collaborations | |
| Participation in projects, networks and consortia |
Yes |
| Funding | |
| Funding status |
Mixed |
| Details | COMMUNAUTE EUROPEENNE (PROJET NEMO) MSD, PMO |
| Governance of the database | |
| Sponsor(s) or organisation(s) responsible | Institut National de la Santé et de la Recherche Médicale |
| Organisation status |
Public |
| Additional contact | |
| Main features | |
| Type of database | |
| Type of database |
Study databases |
| Study databases (details) |
Cohort study |
| Database recruitment is carried out by an intermediary |
A population file |
| Database recruitment is carried out as part of an interventional study |
No |
| Additional information regarding sample selection. | Inclusion method: Prospective Other bodies active in creating this cohort: SSMB |
| Database objective | |
| Main objective | General objective: A prospective evaluation characterising age-related bone loss in men at different skeletal sites. Identification of clinical, biochemical and hormonal determinants of bone loss and fractures with the aid of biochemical markers. |
| Inclusion criteria | Men aged 19 to 85 years old affiliated with the Burgundy Mine Workers' Welfare Society at Monceau-les-Mines (Saône-et-Loire 71) |
| Population type | |
| Age |
Adulthood (19 to 24 years) Adulthood (25 to 44 years) Adulthood (45 to 64 years) Elderly (65 to 79 years) |
| Population covered |
General population |
| Gender |
Male |
| Geography area |
Local |
| French regions covered by the database |
Bourgogne Franche-Comté |
| Detail of the geography area | MONCEAU-LES-MINES AND NEIGHBOURING COMMUNES (SAONE-ET-LOIRE 71) |
| Data collection | |
| Dates | |
| Date of first collection (YYYY or MM/YYYY) | 01/1996 |
| Date of last collection (YYYY or MM/YYYY) | 01/2006 |
| Size of the database | |
| Size of the database (number of individuals) |
[1000-10 000[ individuals |
| Details of the number of individuals | 1040 |
| Data | |
| Database activity |
Current data collection |
| Type of data collected |
Clinical data Declarative data Paraclinical data Biological data |
| Clinical data (detail) |
Direct physical measures Medical registration |
| Declarative data (detail) |
Face to face interview |
| Paraclinical data (detail) | Imaging |
| Biological data (detail) | Type of samples taken: Bone remodelling markers, sex steroid hormones, parathyroid hormone, vitamin D, IGF1 growth factors |
| Presence of a biobank |
Yes |
| Contents of biobank |
Whole blood Serum Plasma Fluids (saliva, urine, amniotic fluid, …) |
| Details of biobank content | Serum bank, plasma bank, WHOLE BLOOD, URINE - 1ST MICTURITION AND 24 HOURS (UNTIL FOLLOW-UP 4) |
| Health parameters studied |
Health event/morbidity Health event/mortality |
| Procedures | |
| Data collection method | Interview: Input from a paper questionnaire (Manual input) with double data entry Clinical examinations: Handwritten (Manual input) with double data entry |
| Participant monitoring |
Yes |
| Details on monitoring of participants | Follow-up duration: 10 years |
| Links to administrative sources |
Yes |
| Linked administrative sources (detail) | SSNB: AFFLIATE DATABASE |
| Promotion and access | |
| Promotion | |
| Link to the document | http://www.ncbi.nlm.nih.gov/pubmed/?term=%28minos+AND+%28Delmas[Author]+OR+Chapurlat+RD[Author]%29%29+OR+11547899[uid] |
| Description | List of publications in Pubmed |
| Access | |
| Terms of data access (charter for data provision, format of data, availability delay) | Data may be used by academic teams Data may be used by industrial teams |
| Access to aggregated data |
Access on specific project only |
| Access to individual data |
Access on specific project only |
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