Latest database descriptions

1) To test the association between constitutional DNA polymorphism, environmental parameters, molecular subtype and clinical data. The inclusion of features of both the tumour and the host will facilitate the discovery of tumourigenesis mechanisms, drugable targets and diagnostic and prognostic biomarkers.
2) To provide insight into the tumour progression knowledge and to help to identify biomarkers by the sequential sampling of recurrent tumors, plasma or urine from individual patients during follow_up.
3) To validate and extend our prior results regarding the molecular subtyping of bladder cancer on a large series of tumors collected prospectively.
4) To facilitate the transfer of study results into clinical practice thanks to the size and bladder cancer representativeness of the cohort.
5) To describe treatment patterns and to assess the direct and indirect costs of bladder cancer. The cost variability will be analyzed to identify the determinants of cost. This evaluation will pave the way for cost-benefit analyses of new biomarkers developed by the consortium.
6) To structure, at the national level, an interdisciplinary bladder cancer network including epidempiologists, bioinformaticians, health economists, molecular biologists, occupational physicians, pathologists and urologists, for coordinated and synergistic research actions and to make a significant contribution to a European multinational cohort and support international studies in genomics, in particular.

Addressing the determinants of health prognosis in obese patients who benefit from bariatric surgery.

The main aim of this study was to assess the addictive behavior of French students’ and identify students having the most at risks practices of BD.
The second objective was to analyze physical and mental health, violence and access to health care in all students.

To describe fertility, involuntary sterility and the use of medically assisted procreation treatment. To determine the influence of environmental factors (including air pollutants) on couples' fertility. To establish a national surveillance system in the field of reproduction and develop new means of studying the relationship between environment and reproduction. To characterise the use of medically assisted procreation (timeline, couples' treatment path). To identify menstrual cycle characteristics and the environmental influence on these characteristics.