Latest database descriptions

The objectives of this study were to describe the children initiating treatment with levetiracetam, the prescribing patterns, and to evaluate the effectiveness of levetiracetam in a real situation in terms of treatment retention for one year.

The primary objective of the study is to verify the absence of accumulation of bismuth in subjects prescribed Pylera®, a pharmacokinetic approach in a real-life setting.

I-VISCONTI is a multicenter, multidisciplinary (clinicians, virologists, immunologists and epidemiologists) pathophysiologic study designed to explore the virological and immunological mechanisms responsible for sustained control of HIV-1 infection after ART interruption in adults or children who started treatment very early in the primary infection or during the chronic phase. I-VISCONTI also aims to identify markers that could be used to identify patients who could reasonably interrupt their antiretroviral treatment.

The main aim of the EPHEGREN study is to assess the pharmacoeconomic impact of different immunosuppressive strategies (IS) on kidney transplant patients from a hospital, health insurance and societal perspective.
The secondary objectives of the EPHEGREN study:
To assess the cost-effectiveness of different preventative and curative strategies for reactivation and cytomegalovirus (CMV) disease in CMV+ kidney transplant patients (serologic status of recipient when receiving transplant) from a hospital, health insurance and societal perspective.
To determine predictive pharmacological factors for long-term renal function outcome.
To determine predictive pharmacological factors for the onset of cancer, diabetes and cardiovascular diseases.
To validate the impact of genetic polymorphisms on metabolic enzymes, membrane transporters and proteins targeting immunosuppressants on exposure and the therapeutic and side effects of treatment.
To prospectively validate urinary biomarker candidates for current or future acute rejection, or for chronic renal allograft dysfunction.