SARCODO - Evaluation of coagulopathy and endothelial dysfunction as a predictive factor for the severity of SARS-CoV-2/COVID-19 infection

Head :
SMADJA David, UMR-S1140 and Biosurgical Research Laboratory (Carpentier Foundation)

Last update : 05/05/2021 | Version : 1 | ID : 73746

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Métadonnées
Identification
General Aspects
Scientific investigator(s) (Contact)
Collaborations
Funding
Governance of the database
Additional contact
Type of database
Database objective
Population type
Dates
Size of the database
Data
Procedures
Promotion
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General
Identification
Detailed name Evaluation of coagulopathy and endothelial dysfunction as a predictive factor for the severity of SARS-CoV-2/COVID-19 infection
Sign or acronym SARCODO
CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation CPP2020-04-048b
General Aspects
Medical area Biology
Hematology
Infectious diseases
Study in connection with Covid-19 Yes
Keywords von Willebrand factor, endothelium, COVID-19, haemostasis
Scientific investigator(s) (Contact)
Name of the director SMADJA
Surname David
Address HEGP, Service d'hématologie, 20 rue Leblanc, 75015 Paris
Phone 33613838972
Email david.smadja@aphp.fr
Unit UMR-S1140 and Biosurgical Research Laboratory (Carpentier Foundation)
Organization Inserm
Collaborations
Funding
Funding status Public
Details ANR SARCODO (France Foundation)
Governance of the database
Sponsor(s) or organisation(s) responsible AP-HP
Organisation status Public
Presence of scientific or steering committees No
Additional contact
Email yannick.vacher@aphp.fr
Main features
Type of database
Type of database Others
Specify Clinical and laboratory database
Database recruitment is carried out as part of an interventional study No
Database objective
Main objective Study the coagulopathy, vascular lesion and markers for tissue distress to characterise the exacerbation of patients with COVID-19 and identify patient populations who will develop or experience exacerbation of a thromboembolic or microvascular process, but also require curative anticoagulation.
Inclusion criteria Patients aged at least 18 years
Hospitalised in an intensive care or medicine department for suspected COVID-19.
Patients covered by a social security regime (other than the state welfare scheme)
Patient having been informed of the study and having given their informed consent in writing, or for whom a family member/trusted person has given their agreement
Population type
Age Adolescence (13 to 18 years)
Adulthood (19 to 24 years)
Adulthood (25 to 44 years)
Adulthood (45 to 64 years)
Elderly (65 to 79 years)
Great age (80 years and more)
Population covered General population
Pathology
Gender Male
Woman
Geography area Regional
French regions covered by the database Île-de-France
Detail of the geography area HEGP and Cochin Hospital
Data collection
Dates
Date of first collection (YYYY or MM/YYYY) 2020
Size of the database
Size of the database (number of individuals) [1000-10 000[ individuals
Details of the number of individuals 1000
Data
Type of data collected Clinical data
Biological data
Clinical data (detail) Direct physical measures
Medical registration
Presence of a biobank Yes
Contents of biobank Whole blood
Plasma
Blood cells isolated
DNA
Procedures
Followed pathology
Promotion and access
Promotion
Link to the document 2020- Debuc et al- SCRR Covid19.pdf
Link to the document 2020- Smadja_Article_Angiopoietin-Covid19-Angiogenesis.pdf
Link to the document 2020- diehl et al- AIC-covid19.pdf
Link to the document 2020- Khider et al-CEC JTH.pdf
Link to the document 2020- Petrazzuolo et al- Oncoimmunology COVID FRP.pdf
Link to the document 2020- bastard et al- Science AutomAb IFN Covid.pdf
Link to the document 2021- Philippe_et_al-Angiogenesis-WILLEBRAND.pdf
Link to the document 2021- Planquette et al- TR- EP Covid.pdf
Link to the document 2020- Guerin et al- SCRR- Article_MultidimensionalProteomicAppro.pdf
Link to the document 2020- Goudot et al- tropo covid-Front Med.pdf
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