CATHY - Thyroid Cancer Study in Calvados, Marne and The Ardennes 
Head :
Guénel Pascal, CESP - Inserm UMR S 1018
Epidémiologie environnementale des cancers de l'adulte
Last update : 09/05/2017 | Version : 1 | ID : 6491
| General | |
| Identification | |
| Detailed name | Thyroid Cancer Study in Calvados, Marne and The Ardennes |
| Sign or acronym | CATHY |
| CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | CNIL : autorisation n° 05-1344 du 2 septembre 2005 CPP (CCPPRB du Kremlin-Boicêtre) : projet N°06-13 / protocole N°C05-55 - Avis favorable du 26 avril 2006 |
| General Aspects | |
| Medical area |
Cancer research |
| Health determinants |
Genetic Geography Occupation Pollution |
| Keywords | Risk, thyroid, exposure, profession, environment, cancer |
| Scientific investigator(s) (Contact) | |
| Name of the director | Guénel |
| Surname | Pascal |
| Address | 16 avenue Paul Vaillant-Couturier, 94807 VILLEJUIF |
| Phone | +33 (0)1 45 59 50 27 |
| pascal.guenel@inserm.fr | |
| Unit |
CESP - Inserm UMR S 1018 Epidémiologie environnementale des cancers de l'adulte |
| Organization | Institut National de la Santé et de la Recherche |
| Collaborations | |
| Funding | |
| Funding status |
Mixed |
| Details | - Institut National Du Cancer - Fondation de France - Institut de veille sanitaire - Institut National de la Santé et de la Recherche Médicale - Ligue contre le Cancer - EDF |
| Governance of the database | |
| Sponsor(s) or organisation(s) responsible | Institut National de la Santé et de la Recherche Médicale |
| Organisation status |
Public |
| Additional contact | |
| Main features | |
| Type of database | |
| Type of database |
Study databases |
| Study databases (details) |
Case control study |
| Database recruitment is carried out by an intermediary |
A selection of health institutions and services |
| Database recruitment is carried out as part of an interventional study |
No |
| Additional information regarding sample selection. | Cases are identified from population registries. Age and sex-matched controls were selected from the general population. |
| Database objective | |
| Main objective | To identify hormonal, reproductive environmental, and lifestyle risk factors of thyroid cancers. |
| Inclusion criteria | - Men or women - adult |
| Population type | |
| Age |
Adulthood (19 to 24 years) Adulthood (25 to 44 years) Adulthood (45 to 64 years) Elderly (65 to 79 years) |
| Population covered |
General population |
| Gender |
Male Woman |
| Geography area |
Departmental |
| French regions covered by the database |
Alsace Champagne-Ardenne Lorraine Normandie |
| Detail of the geography area | France (Calvados, Marne, Ardennes) |
| Data collection | |
| Dates | |
| Date of first collection (YYYY or MM/YYYY) | 2002 |
| Date of last collection (YYYY or MM/YYYY) | 2007 |
| Size of the database | |
| Size of the database (number of individuals) |
[1000-10 000[ individuals |
| Details of the number of individuals | 1400 sujets - 700 cas - 700 témoins |
| Data | |
| Database activity |
Data collection completed |
| Type of data collected |
Clinical data Biological data |
| Clinical data (detail) |
Direct physical measures |
| Biological data (detail) | DNA samples |
| Presence of a biobank |
Yes |
| Contents of biobank |
Buccal cells DNA |
| Details of biobank content | DNA collected from saliva (ORAGENE kits) |
| Health parameters studied |
Health event/morbidity |
| Procedures | |
| Data collection method | By researcher |
| Participant monitoring |
No |
| Links to administrative sources |
No |
| Promotion and access | |
| Promotion | |
| Link to the document | http://adelf.educasante.org/files/oraux/424.pdf |
| Access | |
| Terms of data access (charter for data provision, format of data, availability delay) | To be defined |
| Access to aggregated data |
Access on specific project only |
| Access to individual data |
Access on specific project only |
