Poly - Case-control Study on Thyroid Cancer Risk in French Polynesia
Head :
De Vathaire Florent
Last update : 06/23/2015 | Version : 2 | ID : 6067
| General | |
| Identification | |
| Detailed name | Case-control Study on Thyroid Cancer Risk in French Polynesia |
| Sign or acronym | Poly |
| CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | CNIL |
| General Aspects | |
| Medical area |
Cancer research |
| Pathology (details) | Impact of ESS |
| Health determinants |
Geography Nutrition Pollution |
| Keywords | geographical study, French Polynesia, stable iodine, obesity, nuclear tests, thyroid cancer, case-control study, diet, incidence |
| Scientific investigator(s) (Contact) | |
| Name of the director | De Vathaire |
| Surname | Florent |
| Address | B2M - 114, rue Edouard Vaillant 94805 Villejuif Cedex |
| Phone | + 33 (0)1 42 11 54 57 |
| florent.devathaire@gustaveroussy.fr | |
| Organization | Institut National de la Santé et de la Recherche |
| Collaborations | |
| Funding | |
| Funding status |
Mixed |
| Details | - Directorate of Nuclear Test Centres (DIRCEN) - French National Cancer League - Fondation de France - French Ministry of the Environment |
| Governance of the database | |
| Sponsor(s) or organisation(s) responsible | Institut National de la Santé et de la Recherche Médicale |
| Organisation status |
Public |
| Additional contact | |
| Main features | |
| Type of database | |
| Type of database |
Study databases |
| Study databases (details) |
Case control study |
| Database recruitment is carried out by an intermediary |
A population file An administrative base or a register |
| Database recruitment is carried out as part of an interventional study |
No |
| Additional information regarding sample selection. | Subjects were selected from the cancer registry in French Polynesia. |
| Database objective | |
| Main objective | The objective is to assess the role of nuclear tests on the risk of thyroid cancer and to estimate the risk of cancer in subjects born in French Polynesia by studying 1) the role of certain elements and molecules present in diet, which are suspected of playing their own role in the risk of thyroid cancer, and investigating 2) the role of dietary intake in stable iodine consumption in the risk of thyroid cancer. |
| Inclusion criteria |
- male or female
- subjects - living in French Polynesia |
| Population type | |
| Age |
Adulthood (19 to 24 years) Adulthood (25 to 44 years) Adulthood (45 to 64 years) |
| Population covered |
General population |
| Gender |
Male Woman |
| Geography area |
Regional |
| Detail of the geography area | French Polynesia |
| Data collection | |
| Dates | |
| Date of first collection (YYYY or MM/YYYY) | 1985 |
| Date of last collection (YYYY or MM/YYYY) | 2012 |
| Size of the database | |
| Size of the database (number of individuals) |
[500-1000[ individuals |
| Details of the number of individuals | 602 subjects - 229 differentiated thyroid cancers - 373 controls |
| Data | |
| Database activity |
Current data collection |
| Type of data collected |
Clinical data Declarative data |
| Clinical data (detail) |
Direct physical measures |
| Details of collected clinical data | Data from the pathology and biology laboratories in Mamao Hospital. |
| Declarative data (detail) |
Paper self-questionnaire |
| Details of collected declarative data | Subject dietary data. |
| Presence of a biobank |
No |
| Health parameters studied |
Health event/morbidity Health event/mortality Others |
| Other (detail) | Nutrition |
| Procedures | |
| Participant monitoring |
Yes |
| Links to administrative sources |
No |
| Promotion and access | |
| Promotion | |
| Link to the document | http://onlinelibrary.wiley.com/doi/10.1046/j.1365-3156.2000.00624.x/full |
| Access | |
| Terms of data access (charter for data provision, format of data, availability delay) | To be defined |
| Access to aggregated data |
Access on specific project only |
| Access to individual data |
Access on specific project only |
