EuroSC - The European Schizophrenia Cohort 
Head :
Jean Michel Azorin
Bebbington Paul
Bebbington Paul
Last update : 09/05/2017 | Version : 1 | ID : 73208
| General | |
| Identification | |
| Detailed name | The European Schizophrenia Cohort |
| Sign or acronym | EuroSC |
| CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | CNIL |
| General Aspects | |
| Medical area |
Psychology and psychiatry |
| Pathology (details) | Schizophrenia |
| Health determinants |
Healthcare system and access to health care services Medicine |
| Keywords | schizophrenia, management, treatment, quality of life, care, cost |
| Scientific investigator(s) (Contact) | |
| Name of the director | Jean Michel |
| Surname | Azorin |
| Phone | +33 (0)4 91 74 48 15 |
| Jean-michelRoch.AZORIN@ap-hm.fr jazorin@ap-hm.fr | |
| Organization | AP-HM Southern Regional Hospitals |
| Name of the director | Bebbington |
| Surname | Paul |
| Address |
Wolfson Building 48 Riding House Street London W1W 7EY, UK |
| p.bebbington@ucl.ac.uk | |
| Organization | Royal Free and University College Medical School, UCL |
| Collaborations | |
| Participation in projects, networks and consortia |
Yes |
| Details | EuroSC Research Group (Germany, England, France) |
| Funding | |
| Funding status |
Mixed |
| Details | Lundbeck A/S ; German Federal Ministry of Education and Research |
| Governance of the database | |
| Sponsor(s) or organisation(s) responsible | Royal Free and University College Medical School.. Pour la partie Francaise : Hôpital Sainte Marguerite , Marseille |
| Organisation status |
Public |
| Additional contact | |
| Main features | |
| Type of database | |
| Type of database |
Study databases |
| Study databases (details) |
Cohort study |
| Database recruitment is carried out by an intermediary |
A selection of health institutions and services |
| Database recruitment is carried out as part of an interventional study |
No |
| Database objective | |
| Main objective |
The main aim of EuroSC is to report on the different types of treatment and care, as well as clinical outcome.
Secondary aims include: assessment of treatment requirements in relation to outcome, calculation of resource usage with regards to different care methods and identification of prognostic factors. |
| Inclusion criteria |
Patients between 18 and 64 years old at baseline;
Established schizophrenia diagnosis; Participant consent |
| Population type | |
| Age |
Adulthood (19 to 24 years) Adulthood (25 to 44 years) Adulthood (45 to 64 years) |
| Population covered |
Sick population |
| Gender |
Male Woman |
| Geography area |
International |
| Detail of the geography area | Europe — France (Lille, Lyon, Marseilles, Clermont-Ferrand, Toulon) |
| Data collection | |
| Dates | |
| Date of first collection (YYYY or MM/YYYY) | 1998 |
| Date of last collection (YYYY or MM/YYYY) | 2002 |
| Size of the database | |
| Size of the database (number of individuals) |
[1000-10 000[ individuals |
| Details of the number of individuals | France: 288; UK: 302; Germany: 618 |
| Data | |
| Database activity |
Data collection completed |
| Type of data collected |
Clinical data Declarative data |
| Clinical data (detail) |
Direct physical measures |
| Details of collected clinical data | Psychiatric history, sociodemographic information, diagnosis, treatment, psychiatric and social state (SCAN SCAN, Positive and Negative Syndrome Scale (PANSS), Calgary Depression Scale for Schizophrenia (CDSS), Clinical Global Impression (CGI), Global Assessment of Functioning (GAF), Global Assessment of Relational Functioning (GARF)) medication use and side effects, treatment adherence (Rating of Medication Influences (ROMI) Scale,), healthcare system pathway and usage of service resources. |
| Declarative data (detail) |
Face to face interview |
| Details of collected declarative data | Quality of Life (Medical Outcome Study Short Form 36 (SF36), Social and Occupational Functioning Assessment Scale (SOFAS), Quality of Life Interview (QoLI), EuroQoL) |
| Presence of a biobank |
No |
| Health parameters studied |
Health event/morbidity Health care consumption and services Quality of life/health perception |
| Care consumption (detail) |
Hospitalization Medical/paramedical consultation Medicines consumption |
| Procedures | |
| Data collection method | By medical staff in the centres concerned. |
| Participant monitoring |
Yes |
| Details on monitoring of participants | Every 6 months for 2 years following enrolment. |
| Links to administrative sources |
No |
| Promotion and access | |
| Promotion | |
| Link to the document | http://www.biomedcentral.com/1472-6963/12/269#B4 |
| Link to the document | http://tinyurl.com/PUBMED-EUROSC |
| Access | |
| Terms of data access (charter for data provision, format of data, availability delay) | Contact the scientist in charge. |
| Access to aggregated data |
Access on specific project only |
| Access to individual data |
Access on specific project only |
