SAGE - Susceptibility - Addictions - Genetics - Environment
Head :
Gorwood Philip, HOPITAL SAINTE-ANNE ET INSERM U675
Last update : 07/21/2015 | Version : 2 | ID : 60106
| General | |
| Identification | |
| Detailed name | Susceptibility - Addictions - Genetics - Environment |
| Sign or acronym | SAGE |
| CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | CNIL: 12/10/2006 |
| General Aspects | |
| Medical area |
General practice Immunology Neurology Psychology and psychiatry |
| Health determinants |
Addictions Genetic Nutrition Social and psychosocial factors |
| Keywords | childhood behavioural disorder, toxic, Health episodes, evaluation, general health, consumption, parents |
| Scientific investigator(s) (Contact) | |
| Name of the director | Gorwood |
| Surname | Philip |
| Address | 75674 PARIS PRAIS CEDEX 14 |
| Phone | +33 (0)1 45 65 85 72 |
| p.gorwood@ch-sainte-anne.fr | |
| Unit | HOPITAL SAINTE-ANNE ET INSERM U675 |
| Organization | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - |
| Collaborations | |
| Participation in projects, networks and consortia |
Yes |
| Funding | |
| Funding status |
Mixed |
| Details | Caisse régionale d'assurance maladie de Champagne-Ardenne, Mission Interministérielle de Lutte contre la Drogue et la Toxicomanie, Institut de REcherche sur les Boissons (I.R.E.B), fonds privés |
| Governance of the database | |
| Sponsor(s) or organisation(s) responsible | Inserm |
| Organisation status |
Public |
| Additional contact | |
| Main features | |
| Type of database | |
| Type of database |
Study databases |
| Study databases (details) |
Cohort study |
| Database recruitment is carried out by an intermediary |
A population file |
| Database recruitment is carried out as part of an interventional study |
No |
| Additional information regarding sample selection. | Prospective Inclusion cut-off date: 01/04/2007 Number of required subjects: [1,000-5,000] |
| Database objective | |
| Main objective | General Objective: To evaluate the effect of psychological, genetic and anamnestic variables on addiction at two years Secondary Objectives: - to highlight intermediate traits associated with addictive disorders at two years - to highlight the effect of gene x environment interactions on the development of dependence. |
| Inclusion criteria | Secondary school students and legal age students in the Champagne-Ardennes region who have consented to participate. No exclusion criteria. |
| Population type | |
| Age |
Adulthood (19 to 24 years) |
| Population covered |
General population |
| Gender |
Male Woman |
| Geography area |
Regional |
| French regions covered by the database |
Alsace Champagne-Ardenne Lorraine |
| Detail of the geography area | 20 centres throughout the Champagne-Ardenne region |
| Data collection | |
| Dates | |
| Date of first collection (YYYY or MM/YYYY) | 03/2007 |
| Date of last collection (YYYY or MM/YYYY) | 04/2009 |
| Size of the database | |
| Size of the database (number of individuals) |
[1000-10 000[ individuals |
| Details of the number of individuals | 3046 |
| Data | |
| Database activity |
Current data collection |
| Type of data collected |
Declarative data Biological data |
| Declarative data (detail) |
Paper self-questionnaire |
| Biological data (detail) | Type of samples taken: saliva |
| Presence of a biobank |
Yes |
| Contents of biobank |
DNA |
| Details of biobank content | DNA bank |
| Health parameters studied |
Health event/morbidity |
| Procedures | |
| Data collection method | Self-administered questionnaire: input from a paper questionnaire (Optical input) Biological analysis: direct input |
| Participant monitoring |
Yes |
| Details on monitoring of participants | Follow-up duration: 2 years |
| Links to administrative sources |
Yes |
| Linked administrative sources (detail) | Database used: CRAM |
| Promotion and access | |
| Promotion | |
| Link to the document | http://www.ncbi.nlm.nih.gov/pubmed/?term=sage+AND+Susceptibility+Addiction+Gene+Environment |
| Description | List of publications in Pubmed |
| Access | |
| Terms of data access (charter for data provision, format of data, availability delay) | Data may be used by academic teams. Access according to temporary contract. Data may not be used by industrial teams |
| Access to aggregated data |
Access on specific project only |
| Access to individual data |
Access on specific project only |
