Post-Occupational Surveillance of Exposed Workers /

SPIRALE - Post-Occupational Surveillance of Exposed Workers

Head :

Carton Matthieu, INSERM U687 MIXTE : INSERM ET CNAMTS
Zins Marie, INSERM U687 MIXTE : INSERM, CNAMTS
Goldberg Marcel, INSERM U687 INSERM U687

Last update : 08/18/2015 | Version : 3 | ID : 60127

General
Identification
Detailed name	Post-Occupational Surveillance of Exposed Workers
Sign or acronym	SPIRALE
CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation	CNIL: 27/05/2005
General Aspects
Medical area	Cancer research Occupational Medicine
Health determinants	Occupation
Keywords	health events, mortality, prevention, environment, healthcare system
Scientific investigator(s) (Contact)
Name of the director	Carton
Surname	Matthieu
Address	94800 VILLEJUIF
Phone	+ 33 (0)1 77 74 74 29
Email	matthieu.carton@inserm.fr
Unit	INSERM U687 MIXTE : INSERM ET CNAMTS
Organization	INSERM - Institut National de Santé et Recherche
Name of the director	Zins
Surname	Marie
Address	94800 VILLEJUIF
Phone	+ 33 (0)1 77 74 74 28
Email	marie.zins@inserm.fr
Unit	INSERM U687 MIXTE : INSERM, CNAMTS
Organization	INSERM - Institut National de Santé et Recherche
Name of the director	Goldberg
Surname	Marcel
Address	94800 VILLEJUIF
Phone	+ 33 (0)1 77 74 74 26
Email	marcel.goldberg@inserm.fr
Unit	INSERM U687 INSERM U687
Organization	INSERM - Institut National de Santé et Recherche
Collaborations
Others	Other related cohorts: ESPRI (the same as SPIRALE but for RSI [Social Security Scheme for Independent Workers] artisans (under DST-INVS)).
Funding
Funding status	Public
Details	CNAMTS, INCA.
Governance of the database
Sponsor(s) or organisation(s) responsible	INSERM - Institut National de Santé et Recherche Médicale
Organisation status	Public
Additional contact
Main features
Type of database
Type of database	Study databases
Study databases (details)	Cohort study
Database recruitment is carried out by an intermediary	A population file
Database recruitment is carried out as part of an interventional study	Yes
Details	Performed at individual level
Additional information regarding sample selection.	Prospective. Other bodies active in creating this cohort: HEALTH EXAMINATION CLINICS.
Database objective
Main objective	General objective: to identify retired workers that were exposed to carcinogens throughout their professional life; to inform them of their right to post-occupational medical monitoring and to support them throughout their efforts. Secondary objective: to conduct an epidemiological (cohort) study to describe the long-term health effects of the considered exposures, and to assess the benefits of post-occupational monitoring in terms of health and social awareness.
Inclusion criteria	Occupational exposure to asbestos or wood dust; Insured under the general social security scheme.
Population type
Age	Elderly (65 to 79 years)
Population covered	General population
Gender	Male
Geography area	National
Detail of the geography area	13 metropolitan départements in 2008 (France).
Data collection
Dates
Date of first collection (YYYY or MM/YYYY)	09/2006
Size of the database
Size of the database (number of individuals)	[1000-10 000[ individuals
Details of the number of individuals	2,084
Data
Database activity	Data collection completed
Type of data collected	Clinical data Declarative data
Clinical data (detail)	Direct physical measures Medical registration
Details of collected clinical data	Clinical examination at baseline.
Declarative data (detail)	Paper self-questionnaire Face to face interview
Details of collected declarative data	Self-administered questionnaire at baseline. Information collected by self-administered questionnaire: occupations and sectors occupied, previous treatment for exposure to carcinogens. Interview questionnaire at baseline. Information collected during interview: work calendar, assessment of exposure to asbestos and wood dust, smoking and alcohol consumption.
Presence of a biobank	No
Health parameters studied	Health event/morbidity Health event/mortality
Procedures
Data collection method	Self-administered questionnaire: recorded from a paper questionnaire (optical input). Interview: recorded from paper questionnaire (optical input).
Quality procedure(s) used	Consistency request when entering computer data and after recording computer data. Missing data managed by returning to third party. Other quality procedure(s): analysis of work calenders. Exposure assessments are verified by cross-reference with an occupational exposure matrix. Patients are informed about the use of their data.
Participant monitoring	Yes
Details on monitoring of participants	Annual for SNIIRAM (including PMSI). Every 10 years for mortality (not currently in progress, planned for 2019).
Links to administrative sources	Yes
Linked administrative sources (detail)	PMSI, SNIIRAM, CépiDc.
Promotion and access
Promotion
Link to the document	spirale et espri beh_46_47_2006.pdf
Link to the document	beh_41_42_2007.pdf
Link to the document	rmr373.pdf
Link to the document	1148_ep5-6_315_art8_full.pdf
Link to the document	suivi_post_professionnel.pdf
Link to the document	http://tinyurl.com/HAL-SPIRALE
Description	List of publications in HAL
Link to the document	http://www.ncbi.nlm.nih.gov/pubmed/?term=%28Carton[author]+OR+Zins[author]+OR+Golberg[author]%29+AND+Spirale
Description	List of publications in Pubmed
Access
Terms of data access (charter for data provision, format of data, availability delay)	To be decided if data may be used by academic teams. To be decided if data may be used by industrial teams.
Access to aggregated data	Access on specific project only
Access to individual data	Access on specific project only