SU.VI.MAX 2 - Study of the relations between global food behaviors and/or specific nutritional factors and ageing on a large population of mature adults 
Head :
Hercberg Serge, Unité de Recherche en Epidémiologie Nutritionnele (UREN), U557 Inserm / U1125 Inra / Cnam / Université Paris 13 (Sorbonne Paris-Cité)
Galan Pilar, Unité de Recherche en Epidémiologie Nutritionnele (UREN), U557 Inserm / U1125 Inra / Cnam / Université Paris 13 (Sorbonne Paris-Cité)
Kesse Emmanuelle, Unité de Recherche en Epidémiologie Nutritionnele (UREN), U557 Inserm / U1125 Inra / Cnam / Université Paris 13 (Sorbonne Paris-Cité)
Galan Pilar, Unité de Recherche en Epidémiologie Nutritionnele (UREN), U557 Inserm / U1125 Inra / Cnam / Université Paris 13 (Sorbonne Paris-Cité)
Kesse Emmanuelle, Unité de Recherche en Epidémiologie Nutritionnele (UREN), U557 Inserm / U1125 Inra / Cnam / Université Paris 13 (Sorbonne Paris-Cité)
Last update : 01/01/2019 | Version : 3 | ID : 3916
| General | |
| Identification | |
| Detailed name | Study of the relations between global food behaviors and/or specific nutritional factors and ageing on a large population of mature adults |
| Sign or acronym | SU.VI.MAX 2 |
| CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | CNIL |
| General Aspects | |
| Medical area |
Endocrinology and metabolism General practice Geriatrics |
| Health determinants |
Nutrition |
| Keywords | chronic diseases, Prevention, mortality |
| Scientific investigator(s) (Contact) | |
| Name of the director | Hercberg |
| Surname | Serge |
| Address | 93017 Bobigny |
| Phone | +33 (0)1 48 38 89 32 |
| s.hercberg@uren.smbh.univ-paris13.fr | |
| Unit | Unité de Recherche en Epidémiologie Nutritionnele (UREN), U557 Inserm / U1125 Inra / Cnam / Université Paris 13 (Sorbonne Paris-Cité) |
| Name of the director | Galan |
| Surname | Pilar |
| Address | 93017 Bobigny |
| Phone | +33 (0)1 48 38 89 32 |
| p.galan@uren.smbh.univ-paris13.fr | |
| Unit | Unité de Recherche en Epidémiologie Nutritionnele (UREN), U557 Inserm / U1125 Inra / Cnam / Université Paris 13 (Sorbonne Paris-Cité) |
| Name of the director | Kesse |
| Surname | Emmanuelle |
| Address | 93017 Bobigny |
| Phone | +33 (0)1 48 38 89 32 |
| e.kesse@uren.smbh.univ-paris13.fr | |
| Unit | Unité de Recherche en Epidémiologie Nutritionnele (UREN), U557 Inserm / U1125 Inra / Cnam / Université Paris 13 (Sorbonne Paris-Cité) |
| Collaborations | |
| Funding | |
| Funding status |
Mixed |
| Details | ANR, Inserm, Mederic, IPSEN, Pierre Fabre |
| Governance of the database | |
| Sponsor(s) or organisation(s) responsible | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM |
| Organisation status |
Public |
| Additional contact | |
| Main features | |
| Type of database | |
| Type of database |
Study databases |
| Study databases (details) |
Cohort study |
| Database recruitment is carried out by an intermediary |
An administrative base or a register |
| Database recruitment is carried out as part of an interventional study |
No |
| Additional information regarding sample selection. | Prospective. Other organizations actives in the constitution of the cohort: public health school of Nancy |
| Database objective | |
| Main objective |
General objective: study the relations between global eating behaviors and/or some specific nutritional factors (provisions and status of anti-oxydants, folates, Omega 3 PUFA, energetic and protein provision, etc.) evaluated from data collected between 1994 and 1996 on a large population of mature adults, and:
- The global quality of ageing among this population, evaluated 12 and 15 years later (2006 and 2009) through a global indicator, realized from different components determining successful aging (cognitive state, mood, nutritional status, bone status, balance disorders, sensory disorders, perceived health, integration, social, physical activity, pathologies existence). - Each specific different specific functional component related to the quality of aging: cognitive functions and depression, risk of sarcopenias or osteoporosis, insulin resistance, life quality, chronic diseases (cancers, cataract, macular degeneration). Secondary objective: evaluate the role of oxidative stress, inflammatory status, insulin resistance, some genetic factors implied in the relation between nutritional behaviors, and/or some more specific nutritional factors, and aging quality |
| Inclusion criteria | Voluntary subjects, having participated to the SUI.VI.MAX cohort, and aged between 55 and 70. |
| Population type | |
| Age |
Adulthood (25 to 44 years) Adulthood (45 to 64 years) Elderly (65 to 79 years) |
| Population covered |
General population |
| Gender |
Male Woman |
| Geography area |
National |
| Detail of the geography area | France |
| Data collection | |
| Dates | |
| Date of first collection (YYYY or MM/YYYY) | 2007 |
| Date of last collection (YYYY or MM/YYYY) | 2009 |
| Size of the database | |
| Size of the database (number of individuals) |
[1000-10 000[ individuals |
| Details of the number of individuals | 7000 |
| Data | |
| Database activity |
Data collection completed |
| Type of data collected |
Clinical data Declarative data Paraclinical data Biological data |
| Clinical data (detail) |
Medical registration |
| Details of collected clinical data | Clinical examination at inclusion and during the follow-up. Frequancy of the examination: 2006-2009. Information collected through the clinical examination: nutritional condition, cognitive functions, mood, complete clinical condition, visual and auditive functions, locomotor condition, postural balance, risk of osteoporosis-related fracture, neuropsychological check, life quality. |
| Declarative data (detail) |
Paper self-questionnaire |
| Details of collected declarative data | Clinical examination at inclusion and during the follow-up. Frequancy of the examination: 2006-2009. Information collected through the clinical examination: nutritional condition, cognitive functions, mood, complete clinical condition, visual and auditive functions, locomotor condition, postural balance, risk of osteoporosis-related fracture, neuropsychological check, life quality. |
| Paraclinical data (detail) | Anthropometry |
| Biological data (detail) | Samples: blood, urine |
| Presence of a biobank |
Yes |
| Contents of biobank |
Serum Plasma Blood cells isolated DNA |
| Details of biobank content | Serum bank, DNA bank, pasma bank, cell lines |
| Health parameters studied |
Health event/morbidity Health event/mortality |
| Procedures | |
| Data collection method | - Self-questionnaire of alimentary registration (inclusion): food consumption data collected through an ad hoc self-questionnaire of half-quantitative alimentary frequency. - Other self-questionnaires (inclusion): data concerning life condition and habits, regular medication, vitamin, supplement and mineral use, hormone replacement treatments, medical, personal and family history will be collected through ad hoc questionnaires. - Life quality self-questionnaire (inclusion): particular questionnaire, adapted to aging people, concerning physical activity, budget aspects, nutrition and food preference evolution. - Clinical data collected from the subject (at inclusion and every 6 months during the follow-up): nutritional condition, cognitive functions, mood, complete clinical condition, visual and auditive functions, locomotor condition, postural balance, risk of osteoporosis-related fracture, neuropsychological check,, life quality, anthropometric measures. Self-questionnaire: manual entry. Interviews: paper questionnaire with double data entry. Clinical examination: manual with double data entry. Biological examination: manual with double data entry. |
| Quality procedure(s) used | Coherence request during and after computer data entry. Missing data checked back to the original file or asked back to the patient or a third. Doctors and subjects remainders for follow-up visits. Internal quality audit reports every year. Patients receive information about the use of their data. |
| Participant monitoring |
Yes |
| Details on monitoring of participants | Follow-up duration: 3 years |
| Links to administrative sources |
No |
| Promotion and access | |
| Promotion | |
| Link to the document | http://www.hal.inserm.fr/SUVIMAX |
| Description | List of publications in HAL |
| Link to the document | http://www.ncbi.nlm.nih.gov/pubmed/?term=SUVIMAX+OR+SU.VI.MAX+OR+Suppl%C3%A9mentation+en+Vitamines+et+Min%C3%A9raux+Antioxydants+NOT+animals |
| Description | List of publications in Pubmed |
| Access | |
| Terms of data access (charter for data provision, format of data, availability delay) | Data utilization possible for academic teams and for industrials. |
| Access to aggregated data |
Access on specific project only |
| Access to individual data |
Access on specific project only |
