EPIDOS - Risk Factors for Osteoporotic Fracture 
Head :
Dargent Patricia, U 953
Bréart , U953
Bréart , U953
Last update : 09/05/2017 | Version : 2 | ID : 60041
| General | |
| Identification | |
| Detailed name | Risk Factors for Osteoporotic Fracture |
| Sign or acronym | EPIDOS |
| CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | CNIL |
| General Aspects | |
| Medical area |
Geriatrics Rheumatology |
| Health determinants |
Addictions Genetic Iatrogenic Intoxication Occupation Social and psychosocial factors |
| Keywords | Observed health episodes, bone fractures, falls |
| Scientific investigator(s) (Contact) | |
| Name of the director | Dargent |
| Surname | Patricia |
| Address | 94807 VILLEJUIF |
| Phone | +33 (0)1 45 59 50 05 |
| patricia.dargent@inserm.fr | |
| Unit | U 953 |
| Organization | INSERM |
| Name of the director | Bréart |
| Address | 94807 VILLEJUIF |
| Unit | U953 |
| Organization | INSERM |
| Collaborations | |
| Funding | |
| Funding status |
Public |
| Details | Inserm, MSD |
| Governance of the database | |
| Sponsor(s) or organisation(s) responsible | Institut National de la Santé et de la Recherche Médicale |
| Organisation status |
Public |
| Additional contact | |
| Main features | |
| Type of database | |
| Type of database |
Study databases |
| Study databases (details) |
Cohort study |
| Database recruitment is carried out by an intermediary |
A population file |
| Database recruitment is carried out as part of an interventional study |
No |
| Additional information regarding sample selection. | Prospective |
| Database objective | |
| Main objective | General objective: to study the risk factors for osteoporotic fracture with a focus on femoral neck fracture |
| Inclusion criteria | Women over 75 years old included in electoral registers with no prior femoral fracture |
| Population type | |
| Age |
Great age (80 years and more) |
| Population covered |
General population |
| Gender |
Woman |
| Geography area |
National |
| Detail of the geography area | Multicentric cohort throughout France (5 centres): Amiens, Lyon, Montpellier, Toulouse, Paris |
| Data collection | |
| Dates | |
| Date of first collection (YYYY or MM/YYYY) | 01/1992 |
| Date of last collection (YYYY or MM/YYYY) | 12/1998 |
| Size of the database | |
| Size of the database (number of individuals) |
[1000-10 000[ individuals |
| Details of the number of individuals | 7575 |
| Data | |
| Database activity |
Data collection completed |
| Type of data collected |
Clinical data Declarative data Paraclinical data Biological data |
| Clinical data (detail) |
Direct physical measures Medical registration |
| Declarative data (detail) |
Paper self-questionnaire |
| Paraclinical data (detail) | Imaging, dual-energy X-ray absorptiometry, ultrasound measurements of bone mineral density |
| Biological data (detail) | Type of samples taken: for femoral neck fracture and case-control sample: analysis of bone metabolism biomarkers |
| Presence of a biobank |
Yes |
| Contents of biobank |
Serum Fluids (saliva, urine, amniotic fluid, …) |
| Details of biobank content | Serum bank, urine |
| Health parameters studied |
Health event/morbidity Health event/mortality |
| Procedures | |
| Data collection method | Self-administered questionnaire: double data entry from a paper questionnaire Interview: double data entry from a paper questionnaire Clinical Examinations: handwritten with double data entry |
| Participant monitoring |
Yes |
| Details on monitoring of participants | Follow-up duration: 4 years |
| Links to administrative sources |
Yes |
| Linked administrative sources (detail) | CépiDc, RNIPP |
| Promotion and access | |
| Promotion | |
| Link to the document | http://tinyurl.com/HAL-EPIDOS |
| Description | List of publications in HAL |
| Link to the document | http://tinyurl.com/Pubmed-EPIDOS |
| Description | List of publications in Pubmed |
| Access | |
| Terms of data access (charter for data provision, format of data, availability delay) | Data may be used by academic teams Data may not be used by industrial teams Access subject to detailed request sent to the Scientific Committee |
| Access to aggregated data |
Access on specific project only |
| Access to individual data |
Access on specific project only |
