RIC-Mel Network - Network for Research and Clinical Investigation on Melanoma - French national cohort of melanoma patients
Head :
Pr Dréno Brigitte, CRCINA - Unité Inserm U1232 - Responsable Equipe 2 "Clinical and translational research in skin cancer"
Pr Lebbe Céleste
Pr Lebbe Céleste
Last update : 11/05/2020 | Version : 5 | ID : 5135
| General | |
| Identification | |
| Detailed name | Network for Research and Clinical Investigation on Melanoma - French national cohort of melanoma patients |
| Sign or acronym | RIC-Mel Network |
| CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | CNIL: EGY/EM/AR124131 |
| General Aspects | |
| Medical area |
Cancer research Dermatology, venereology |
| Pathology (details) | Melanoma |
| Keywords | Melanoma, network, cohort, epidemiology, preclinical to phase III studies, national, european and international instances, fondamental and translational research. |
| Scientific investigator(s) (Contact) | |
| Name of the director | Pr Dréno |
| Surname | Brigitte |
| Address |
CHU de Nantes Service de Dermatologie Site Hôtel Dieu 1, place Alexis Ricordeau 44093 Nantes cedex 01 |
| Phone | - |
| brigitte.dreno@atlanmed.fr | |
| Unit | CRCINA - Unité Inserm U1232 - Responsable Equipe 2 "Clinical and translational research in skin cancer" |
| Organization | Centre de Recherche en Cancérologie et Immunologie Nantes Angers |
| Name of the director | Pr Lebbe |
| Surname | Céleste |
| Address |
Assistance Publique des Hôpitaux de Paris Hôpital Saint Louis Service de Dermatologie 1, avenue Claude Vellefaux 75010 Paris |
| Phone | - |
| celeste.lebbe@sls.aphp.fr | |
| Organization | Hôpital Saint-Louis (AP-HP) |
| Collaborations | |
| Participation in projects, networks and consortia |
Yes |
| Details | Our partners : the Cancerology Group (GCC) of the French Society of Dermatology (SFD), the clinico-biologico-radiological database MELBASE, the Ile de France Melanoma network, the Far West Biotherapies and Researches in Dermatology network (BIORDERM), the West Melanoma Network and the patients association AMESA. |
| Funding | |
| Funding status |
Mixed |
| Details | - |
| Governance of the database | |
| Sponsor(s) or organisation(s) responsible | CHU de Nantes - RIC-Mel coordinating center |
| Organisation status |
Public |
| Sponsor(s) or organisation(s) responsible | Cancerology Group (GCC) of the French Society of Dermatology (SFD) |
| Organisation status |
Public |
| Presence of scientific or steering committees |
Yes |
| Additional contact | |
| Name of the contact | Varey (Chef de projet) |
| Surname | Emilie |
| Address |
CHU de Nantes - Hôtel Dieu 1, place Alexis Ricordeau 44093 NANTES Cedex 01 |
| Phone | 02 40 08 78 85 |
| emilie.varey@chu-nantes.fr | |
| Organization | CHU de Nantes |
| Main features | |
| Type of database | |
| Type of database |
Study databases |
| Study databases (details) |
Cohort study |
| Database recruitment is carried out by an intermediary |
A selection of health institutions and services |
| Database recruitment is carried out as part of an interventional study |
No |
| Additional information regarding sample selection. | After 7 years in existence, 23,971 patients have been included in database by our 49 participating centers. |
| Database objective | |
| Main objective |
- To federate the clinical cancerology and dermatology sites as well as the existing networks in melanoma around a common database,
- To be a preferred interlocutor for the industry, - To ensure close interaction between all the hospital disciplines involved in melanoma evolution, - To ensure the functioning of a clinica ldatabase, - To ensure interactions between clinical and translational research as well as to support basic research. |
| Inclusion criteria | Patients with melanoma, regardless of the location of the primary tumour (cutaneous, mucosal, ocular or unknown) and the stage, and who have accepted to participate. |
| Population type | |
| Age |
Adolescence (13 to 18 years) Adulthood (19 to 24 years) Adulthood (25 to 44 years) Adulthood (45 to 64 years) Elderly (65 to 79 years) Great age (80 years and more) |
| Population covered |
Sick population |
| Pathology | C00-C97 - Malignant neoplasms |
| Gender |
Male Woman |
| Geography area |
National |
| Detail of the geography area | France |
| Data collection | |
| Dates | |
| Date of first collection (YYYY or MM/YYYY) | March 2012 |
| Size of the database | |
| Size of the database (number of individuals) |
Greater than 20 000 individuals |
| Details of the number of individuals | 23,971 patients (1 April, 2019) |
| Data | |
| Database activity |
Current data collection |
| Type of data collected |
Clinical data |
| Clinical data (detail) |
Direct physical measures Medical registration |
| Details of collected clinical data | Data relating to the primitiv tumour, disease evolution (stage, treatments...) until death. |
| Presence of a biobank |
No |
| Health parameters studied |
Health event/morbidity Health event/mortality |
| Procedures | |
| Data collection method | Data are collected during patient follow-up, after expressing its consent |
| Participant monitoring |
Yes |
| Details on monitoring of participants | Patients come as part of their usual medical care. The updating of data only occurs in case of disease progression and until the death. |
| Links to administrative sources |
No |
| Promotion and access | |
| Promotion | |
| Link to the document | Plaquette_informative_du_réseau_RIC-Mel,RIC-Mel-DI-002,v.07.pdf |
| Link to the document | Book_académique_RIC-Mel_CID_2016.pdf |
| Description | Academic book oh the RIC-Mel network created for the Cohort Innovation Day 2016, organised byAVIESAN and ARIIS with the support of INSERM Transfert |
| Link to the document | Poster_IID_DRAFT_5.pdf |
| Description | Poster presented at the International Investigative Dermatology congress in 2018 |
| Other information | First publication : Dalle S. et al., Management of adjuvant settings for Stage III melanoma patients in France prior to checkpoint inhibitors: epidemiological data from the RIC-Mel database. Eur J Dermatol . 2020, 30(4):389-396 |
| Access | |
| Presence of document that lists variables and coding procedures |
Yes |
| Terms of data access (charter for data provision, format of data, availability delay) |
Please contact :
Mr Amir KHAMMARI Deputy coordinator of the RIC-Mel network Tel. : +33 2.40.08.32.80 Mail : amir.khammari@chu-nantes.fr Mrs Emilie VAREY Project manager of the RIC-Mel network Tel. : +33 2.40.08.78.85 Mail : emilie.varey@chu-nantes.fr |
| Access to aggregated data |
Access on specific project only |
| Access to individual data |
No access |
