ATLANTIS - Long term observational study on the therapeutic management of knee osteoarthritis by general practitioners 
Head :
Payen-Champenois Catherine, Bristol-Myers Squibb
Schmidely Nathalie, Bristol-Myers Squibb
Schmidely Nathalie, Bristol-Myers Squibb
Last update : 09/05/2017 | Version : 1 | ID : 121
| General | |
| Identification | |
| Detailed name | Long term observational study on the therapeutic management of knee osteoarthritis by general practitioners |
| Sign or acronym | ATLANTIS |
| CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | CNIL n°903352 (22/11/2003) |
| General Aspects | |
| Medical area |
Rheumatology |
| Others (details) | gonarthrosis, Arthrosis |
| Keywords | therapeutic management, paracetamol, patient reported outcomes |
| Scientific investigator(s) (Contact) | |
| Name of the director | Payen-Champenois |
| Surname | Catherine |
| Address | 3, rue J. Monnier - 92500 Rueil Malmaison |
| Phone | +33 (0)1 58 83 60 00 |
| catherine.payen-champenois@bms.com | |
| Unit | Bristol-Myers Squibb |
| Name of the director | Schmidely |
| Surname | Nathalie |
| Address | 3, rue J. Monnier - 92500 Rueil Malmaison |
| Phone | +33 (0)1 58 83 60 00 |
| nathalie.schmidely@bms.com | |
| Unit | Bristol-Myers Squibb |
| Collaborations | |
| Funding | |
| Funding status |
Private |
| Details | Bristol-Myers Squibb |
| Governance of the database | |
| Sponsor(s) or organisation(s) responsible | Bristol-Myers Squibb (BMS) |
| Organisation status |
Private |
| Additional contact | |
| Main features | |
| Type of database | |
| Type of database |
Study databases |
| Study databases (details) |
Cohort study |
| Database recruitment is carried out by an intermediary |
A selection of health care professionals |
| Database recruitment is carried out as part of an interventional study |
No |
| Additional information regarding sample selection. | Random sampling in clusters |
| Database objective | |
| Main objective |
Evaluate, in general practice, the change in the first-line therapeutic strategy in patients suffering from knee osteoarthritis, over one year, specially: - Evaluate the percentage of patients treated with each therapeutic modality at the end of the one year observation period. - Describe the modifications implemented in the therapeutic management and identify the reasons justifying these modifications. |
| Inclusion criteria |
1. Males or females 50 years or older suffering from symptomatic osteoarthritis of the knee 2. Not treated over the last 6 months for this pathology (non-pharmaceutical treatments and self-medication by analgesics or NSAIDs at low doses will be allowed). 3. For whom the physician will have decided to initiate a first-line treatment in line with the recommendations of EULAR 2000-2003 (paracetamol - systematically taken at a dose of 3 to 4g/d - as pharmacological monotherapy in combination with non-pharmaceutical treatments). |
| Population type | |
| Age |
Adulthood (19 to 24 years) Adulthood (25 to 44 years) Adulthood (45 to 64 years) Elderly (65 to 79 years) Great age (80 years and more) |
| Population covered |
Sick population |
| Gender |
Male Woman |
| Geography area |
International |
| Detail of the geography area | France and Spain |
| Data collection | |
| Dates | |
| Date of first collection (YYYY or MM/YYYY) | 2003 |
| Date of last collection (YYYY or MM/YYYY) | 2006 |
| Size of the database | |
| Size of the database (number of individuals) |
[1000-10 000[ individuals |
| Details of the number of individuals | 1114 (586 in France, 528 in Spain) |
| Data | |
| Database activity |
Data collection completed |
| Type of data collected |
Clinical data Declarative data |
| Clinical data (detail) |
Direct physical measures Medical registration |
| Declarative data (detail) |
Face to face interview |
| Presence of a biobank |
No |
| Health parameters studied |
Health care consumption and services Quality of life/health perception |
| Care consumption (detail) |
Hospitalization Medical/paramedical consultation Medicines consumption |
| Procedures | |
| Data collection method | paper case report form |
| Participant monitoring |
Yes |
| Details on monitoring of participants | M3, M6, M9, M12 |
| Links to administrative sources |
No |
| Promotion and access | |
| Promotion | |
| Access | |
| Terms of data access (charter for data provision, format of data, availability delay) | Publications |
| Access to aggregated data |
Access on specific project only |
| Access to individual data |
Access on specific project only |
