- Cross-sectional study of the influence of exposure to glycol ethers on semen quality 
Head :
Multigner Luc, Inserm U625
Last update : 10/20/2017 | Version : 1 | ID : 6737
| General | |
| Identification | |
| Detailed name | Cross-sectional study of the influence of exposure to glycol ethers on semen quality |
| CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | CNIL |
| General Aspects | |
| Medical area |
Disability/handicap Endocrinology and metabolism Occupational Medicine |
| Pathology (details) | male infertility |
| Health determinants |
Genetic Intoxication Occupation Pollution |
| Keywords | glycol ethers, sperm, semen, Paris, occupational exposure, toxicology |
| Scientific investigator(s) (Contact) | |
| Name of the director | Multigner |
| Surname | Luc |
| Address |
263 Avenue du Général Leclerc - Campus de Beaulieu - BAT 13 - 35042 RENNES |
| Phone | +33 (0)2 23 23 69 11 |
| luc.multigner@inserm.fr | |
| Unit | Inserm U625 |
| Organization | Institut National de la Santé et de la Recherche Médicale, Université Rennes |
| Collaborations | |
| Funding | |
| Funding status |
Public |
| Details | Institut National de la Santé et de la Recherche Médicale - Ministry of the Environment |
| Governance of the database | |
| Sponsor(s) or organisation(s) responsible | Institut National de la Santé et de la Recherche Médicale |
| Organisation status |
Public |
| Sponsor(s) or organisation(s) responsible | Université Rennes 1 |
| Organisation status |
Public |
| Additional contact | |
| Main features | |
| Type of database | |
| Type of database |
Study databases |
| Study databases (details) |
Not-repeated cross-sectional studies (except case control studies) |
| Database recruitment is carried out by an intermediary |
A population file |
| Database recruitment is carried out as part of an interventional study |
No |
| Additional information regarding sample selection. | The sample is made up of employees of the city of Paris. Men who do not have risk factors for infertility and who have not been exposed to agents that can alter semen quality other than glycol ethers were selected. |
| Database objective | |
| Main objective | To research the effect of past and current exposure to glycol ethers on semen quality. |
| Inclusion criteria |
- homme
- âgé entre 20 et 55 ans - employé de la ville de Paris - n’ayant pas de facteurs de risque d’infertilité |
| Population type | |
| Age |
Adulthood (19 to 24 years) Adulthood (25 to 44 years) Adulthood (45 to 64 years) |
| Population covered |
General population |
| Pathology | |
| Gender |
Male |
| Geography area |
Local |
| French regions covered by the database |
Île-de-France |
| Detail of the geography area | Paris |
| Data collection | |
| Dates | |
| Date of first collection (YYYY or MM/YYYY) | 2000 |
| Date of last collection (YYYY or MM/YYYY) | 2001 |
| Size of the database | |
| Size of the database (number of individuals) |
< 500 individuals |
| Details of the number of individuals | 109 |
| Data | |
| Database activity |
Data collection completed |
| Type of data collected |
Declarative data Biological data |
| Declarative data (detail) |
Paper self-questionnaire |
| Details of collected declarative data | Questioned regarding their career path over the course of 1999-2000 and regarding the products handled in the context of their professional or non-professional activities. |
| Biological data (detail) | Seminogram |
| Presence of a biobank |
No |
| Health parameters studied |
Others |
| Other (detail) | Sperm quality |
| Procedures | |
| Data collection method | Collection of data on the chemical composition of the products used by the city of Paris. An industrial health officer validated the correspondence between the activities described by the participants and the categories of products used. |
| Participant monitoring |
No |
| Followed pathology | |
| Links to administrative sources |
No |
| Promotion and access | |
| Promotion | |
| Link to the document | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2078482/#__ffn_sectitle |
| Description | Glycol ethers and semen quality: a cross‐sectional study among male workers in the Paris Municipality |
| Link to the document | http://www.ncbi.nlm.nih.gov/pubmed/?term=Glycol+ethers+AND+semen+AND+Paris+AND+Multigner+L+[Author] |
| Description | List of publications in Pubmed |
| Access | |
| Terms of data access (charter for data provision, format of data, availability delay) | Contact the scientist in charge |
| Access to aggregated data |
Access on specific project only |
| Access to individual data |
Access on specific project only |
