MAP-IDM - Identification of Molecular Markers of Sudden Death at Acute Phase of Myocardial Infarction
Head :
Chevalier Philippe, CENTRE NATIONAL DE RÉFÉRENCE DES TROUBLES DU RYTHME CARDIAQUE D'ORIGINE HÉRÉDITAIRE
SERVICE DE RYTHMOLOGIE
Last update : 06/30/2014 | Version : 1 | ID : 60157
| General | |
| Identification | |
| Detailed name | Identification of Molecular Markers of Sudden Death at Acute Phase of Myocardial Infarction |
| Sign or acronym | MAP-IDM |
| CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | Accord CNIL : 21/12/2007 |
| General Aspects | |
| Medical area |
Cardiology |
| Health determinants |
Occupation |
| Others (details) | Myocardial infarction |
| Keywords | sudden death, acute occlusion, coronary artery, ventricular rhythm disorder, ventricular arrhythmia, Health episodes, hospitalisation |
| Scientific investigator(s) (Contact) | |
| Name of the director | Chevalier |
| Surname | Philippe |
| Address | 69677 LYON |
| Phone | + 33 (0)4 72 35 73 81 |
| elodie.morel01@chu-lyon.fr | |
| Unit |
CENTRE NATIONAL DE RÉFÉRENCE DES TROUBLES DU RYTHME CARDIAQUE D'ORIGINE HÉRÉDITAIRE SERVICE DE RYTHMOLOGIE |
| Organization | Hospices civils de |
| Collaborations | |
| Participation in projects, networks and consortia |
Yes |
| Funding | |
| Funding status |
Public |
| Details | PHRC NATIONAL 2006 |
| Governance of the database | |
| Sponsor(s) or organisation(s) responsible | Hospices civils de Lyon |
| Organisation status |
Public |
| Additional contact | |
| Main features | |
| Type of database | |
| Type of database |
Study databases |
| Study databases (details) |
Case control study |
| Database recruitment is carried out by an intermediary |
A selection of health institutions and services |
| Database recruitment is carried out as part of an interventional study |
No |
| Additional information regarding sample selection. | Inclusion method: Prospective |
| Database objective | |
| Main objective | General objective: To identify predisposing factors of ventricular fibrillation at the acute phase of myocardial infarct: to demonstrate that ventricular fibrillation at the acute phase of myocardial infarction follows a polygenic determinism. |
| Inclusion criteria | Patients admitted to intensive care unit for myocardial infarction. 2 groups: - patients with cardiac arrest by ventricular fibrillation at the acute phase of myocardial infarction; - patients with no ventricular fibrillation at the acute phase of myocardial infarction. |
| Population type | |
| Age |
Adulthood (19 to 24 years) Adulthood (25 to 44 years) Adulthood (45 to 64 years) Elderly (65 to 79 years) Great age (80 years and more) |
| Population covered |
General population |
| Gender |
Male Woman |
| Geography area |
International |
| Detail of the geography area | Multicentric cohort (46 centres) Geographical area covered: FRANCE, SWITZERLAND, BELGIUM |
| Data collection | |
| Dates | |
| Date of first collection (YYYY or MM/YYYY) | 12/2007 |
| Date of last collection (YYYY or MM/YYYY) | 11/2010 |
| Size of the database | |
| Size of the database (number of individuals) |
[500-1000[ individuals |
| Details of the number of individuals | 800 |
| Data | |
| Database activity |
Data collection completed |
| Type of data collected |
Clinical data Biological data |
| Clinical data (detail) |
Direct physical measures Medical registration |
| Biological data (detail) | Type of samples taken: 3 EDTA 7cc tubes |
| Presence of a biobank |
Yes |
| Contents of biobank |
DNA |
| Details of biobank content | DNA bank |
| Health parameters studied |
Health event/morbidity Health event/mortality |
| Procedures | |
| Data collection method | Clinical examination: Handwritten (manual input) Biological Analysis: Handwritten (manual input) and double data entry |
| Participant monitoring |
Yes |
| Details on monitoring of participants | Follow-up duration: 6 months |
| Links to administrative sources |
No |
| Promotion and access | |
| Promotion | |
| Link to the document | http://www.chu-lyon.fr/web/attached_file/chiffres_pam_cpmh_2013.pdf?ComponentId |
| Access | |
| Terms of data access (charter for data provision, format of data, availability delay) | To be decided if data may be used by academic teams Data may not be used by industrial teams |
| Access to aggregated data |
Access on specific project only |
| Access to individual data |
Access on specific project only |
