HCC - Hepatocellular Carcinoma 
Head :
Stücker Isabelle
Last update : 09/05/2017 | Version : 1 | ID : 6466
| General | |
| Identification | |
| Detailed name | Hepatocellular Carcinoma |
| Sign or acronym | HCC |
| CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | Accord CNIL |
| General Aspects | |
| Medical area |
Cancer research Hematology |
| Health determinants |
Addictions Genetic Geography Social and psychosocial factors |
| Others (details) | Liver cancer, cirrhosis, hepatocellular carcinoma |
| Keywords | Hepatitis, markers, multifactorial, aflatoxin, polymorphisms, alcohol |
| Scientific investigator(s) (Contact) | |
| Name of the director | Stücker |
| Surname | Isabelle |
| Address | 16 Avenue Paul Vaillant Couturier, 94807 VILLEJUIF |
| Phone | +33 (0)1 45 59 50 33 |
| isabelle.stucker@inserm.fr | |
| Organization | Institut National de la Santé et de la Recherche |
| Collaborations | |
| Funding | |
| Funding status |
Private |
| Details | Fondation de France |
| Governance of the database | |
| Sponsor(s) or organisation(s) responsible | Institut National de la Santé et de la Recherche Médicale |
| Organisation status |
Public |
| Additional contact | |
| Main features | |
| Type of database | |
| Type of database |
Study databases |
| Study databases (details) |
Case control study |
| Database recruitment is carried out by an intermediary |
A selection of health institutions and services |
| Database recruitment is carried out as part of an interventional study |
No |
| Additional information regarding sample selection. | Random variables For 299 subjects with: - 165 with hepatocellular carcinoma - 134 with cirrhosis of the liver |
| Database objective | |
| Main objective | To evaluate the role of UDP-glucuronosyltransferase enzymes in hepatocellular carcinoma. |
| Inclusion criteria | - Men - adult - below 75 years of age - born in Europe |
| Population type | |
| Age |
Adulthood (19 to 24 years) Adulthood (25 to 44 years) Adulthood (45 to 64 years) Elderly (65 to 79 years) |
| Population covered |
Sick population |
| Gender |
Male |
| Geography area |
National |
| Detail of the geography area | France (3 hospitals in Paris and one hospital in Nancy) |
| Data collection | |
| Dates | |
| Date of first collection (YYYY or MM/YYYY) | 03/2000 |
| Date of last collection (YYYY or MM/YYYY) | 08/2003 |
| Size of the database | |
| Size of the database (number of individuals) |
< 500 individuals |
| Details of the number of individuals | 441 - 299 cas - 142 témoins |
| Data | |
| Database activity |
Data collection completed |
| Type of data collected |
Clinical data Declarative data Biological data |
| Clinical data (detail) |
Medical registration |
| Declarative data (detail) |
Paper self-questionnaire Face to face interview |
| Biological data (detail) | - DNA - test for presence of virus marker |
| Presence of a biobank |
No |
| Health parameters studied |
Health event/morbidity Health event/mortality Health care consumption and services |
| Care consumption (detail) |
Hospitalization Medical/paramedical consultation Medicines consumption |
| Procedures | |
| Participant monitoring |
Yes |
| Links to administrative sources |
No |
| Promotion and access | |
| Promotion | |
| Link to the document | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213656/?tool |
| Access | |
| Terms of data access (charter for data provision, format of data, availability delay) | To decided by the scientist in charge |
| Access to aggregated data |
Access on specific project only |
| Access to individual data |
Access on specific project only |
