AEPEI - Repeated Cross-Sectional Study from The Association for The Study and Prevention of Infective Endocarditis 
Head :
Duval Xavier, CIC7 CIC BICHAT Recherche clinique : Cardio-vasculaire, pneumologie, diabétologie, maladies infectieusesU738 Modèles et méthodes de l'évaluation thérapeutique des maladies chroniquesÉquipe: Modélisation biostatistique et pharmacométrie
Last update : 12/01/2018 | Version : 1 | ID : 7238
| General | |
| Identification | |
| Detailed name | Repeated Cross-Sectional Study from The Association for The Study and Prevention of Infective Endocarditis |
| Sign or acronym | AEPEI |
| General Aspects | |
| Medical area |
Cardiology |
| Health determinants |
Genetic Medicine |
| Keywords | prospective observational study, incidence, assessment |
| Scientific investigator(s) (Contact) | |
| Name of the director | Duval |
| Surname | Xavier |
| Address | 46 rue Henri Huchard 11ème étage aile nord 75877 PARIS CEDEX 18 |
| Phone | +33 (0)1 40 25 71 35 |
| xavier.duval@bch.aphp.fr | |
| Unit | CIC7 CIC BICHAT Recherche clinique : Cardio-vasculaire, pneumologie, diabétologie, maladies infectieusesU738 Modèles et méthodes de l'évaluation thérapeutique des maladies chroniquesÉquipe: Modélisation biostatistique et pharmacométrie |
| Organization | Assistance Publique des Hopitaux de Paris ; Institut National de la Santé et de la Recherche |
| Collaborations | |
| Funding | |
| Funding status |
Mixed |
| Details | - National Education Association for Therapeutic Teaching - French Language Society of Infectious Disease - French Microbiology Society - French National Society of Internal Medicine - French Language Resuscitation Society - French Society of Gerontology - French Society of Cardiology - French Society of Thoracic and Cardiovascular Surgery - French Society of Anaesthesia-Resuscitation - French Federation of Cardiology - French National Institute of Health and Medical Research - Ministry of Health (Department of Clinical Research and Innovation) - European Society of Clinical Microbiology and Infectious Diseases - Novartis Laboratories - Besançon University Hospital - Edwards Lifesciences - Sanofi-Aventis. |
| Governance of the database | |
| Sponsor(s) or organisation(s) responsible | Assistance Publique des Hopitaux de Paris |
| Organisation status |
Public |
| Sponsor(s) or organisation(s) responsible | Institut National de la Santé et de la Recherche Médicale |
| Organisation status |
Public |
| Additional contact | |
| Main features | |
| Type of database | |
| Type of database |
Study databases |
| Study databases (details) |
Repeated cross-sectional studies (except case control studies) |
| Database recruitment is carried out by an intermediary |
A selection of health institutions and services |
| Database recruitment is is made on the basis of: |
Medication(s) taken |
| Database recruitment is carried out as part of an interventional study |
No |
| Additional information regarding sample selection. | Cases are reported by fax, email, post or online. Case reports are carried out by clinicians treating the patient, microbiologists and echocardiography professionals. |
| Database objective | |
| Main objective | To describe trends in incidence, epidemiological, clinical, microbiological and prognostic factors, as well as surgical treatment procedures for infective endocarditis in France in 2008, in relation to 1991 and 1999. |
| Inclusion criteria |
- Male and female;
- Over 18 years old; - Treated for infective endocarditis. |
| Population type | |
| Age |
Adulthood (19 to 24 years) Adulthood (25 to 44 years) Adulthood (45 to 64 years) |
| Population covered |
Sick population |
| Gender |
Male Woman |
| Geography area |
National |
| Detail of the geography area | France (Franche-Comté, Ille-et-Vilaine, Languedoc-Roussillon, Lorraine, Marne, Ile de France and Rhône-Alpes). |
| Data collection | |
| Dates | |
| Date of first collection (YYYY or MM/YYYY) | 1991 |
| Date of last collection (YYYY or MM/YYYY) | 12/2008 |
| Size of the database | |
| Size of the database (number of individuals) |
[500-1000[ individuals |
| Details of the number of individuals | 993: - 323 (1991) - 331 (1999) - 339 (2008). |
| Data | |
| Database activity |
Data collection completed |
| Type of data collected |
Declarative data Paraclinical data Biological data |
| Declarative data (detail) |
Paper self-questionnaire |
| Details of collected declarative data | Questionnaire completed by treating physician. - Chronology of initial symptoms and hospitalisation - cardiac history- pre-existing associated illnesses - risk factors and habitus - origin of infection and clinical symptoms. |
| Paraclinical data (detail) | - Echocardiography (only preoperative echocardiography) - abdominal ultrasound - abdominal CT - chest scan - brain scan - MRI - dental panoramic orthopantomogram - colonoscopy - coronary angiography. |
| Biological data (detail) | - Blood cultures - serology - valve samples. |
| Presence of a biobank |
Yes |
| Contents of biobank |
Whole blood Others |
| Details of biobank content | Blood cultures, serology, valve samples. |
| Health parameters studied |
Health event/morbidity Health event/mortality Health care consumption and services |
| Care consumption (detail) |
Hospitalization Medical/paramedical consultation Medicines consumption |
| Procedures | |
| Data collection method | Slips for collected clinical and microbiology data are respectively sent to the clinician responsible for the patient and the centre's microbiologist after each report. One of the physicians in the coordination group is responsible for data collection quality in each region. |
| Participant monitoring |
No |
| Links to administrative sources |
No |
| Promotion and access | |
| Promotion | |
| Link to the document | http://www.sciencedirect.com/science/article/pii/S0735109712009849 |
| Link to the document | http://eurheartj.oxfordjournals.org/content/28/1/59.long |
| Link to the document | http://cid.oxfordjournals.org/content/39/1/68.long |
| Access | |
| Terms of data access (charter for data provision, format of data, availability delay) | Contact the scientist in charge. |
| Access to aggregated data |
Access on specific project only |
| Access to individual data |
Access on specific project only |
