REAL.FR - Longitudinal Study on Patients in Alzheimer's Disease Network 
Head :
Vellas Bruno, Inserm U 1027
Last update : 09/05/2017 | Version : 2 | ID : 8787
| General | |
| Identification | |
| Detailed name | Longitudinal Study on Patients in Alzheimer's Disease Network |
| Sign or acronym | REAL.FR |
| CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | CNIL approval. |
| General Aspects | |
| Medical area |
Geriatrics Neurology |
| Health determinants |
Genetic |
| Keywords | healthcare sector, institutionalisation, network |
| Scientific investigator(s) (Contact) | |
| Name of the director | Vellas |
| Surname | Bruno |
| Address | CHU de Toulouse GERONTOPOLE 170, Avenue de Caselardit TSA 40031 31059 Toulouse Cédex 09 |
| Phone | +33 (0)5 61 77 64 25 |
| vellas.b@chu-toulouse.fr | |
| Unit | Inserm U 1027 |
| Organization | CHU de |
| Collaborations | |
| Funding | |
| Funding status |
Public |
| Details | Ministry of Health. |
| Governance of the database | |
| Sponsor(s) or organisation(s) responsible | CHU de Toulouse |
| Organisation status |
Public |
| Additional contact | |
| Main features | |
| Type of database | |
| Type of database |
Study databases |
| Study databases (details) |
Longitudinal study (except cohorts) |
| Database recruitment is carried out by an intermediary |
A selection of health institutions and services |
| Database recruitment is carried out as part of an interventional study |
No |
| Additional information regarding sample selection. | The study population consists of patients with Alzheimer's-type dementia. |
| Database objective | |
| Main objective |
To ensure regular monitoring of the patient and those close to them in order to assess the cognitive and non-cognitive aspects of the disease.
To analyse treatment methods, as well as drug- and non-drug-related therapy for elderly people with AD across a national sample with diverse socio-cultural contexts. To identify potential treatment issues, such as repeated hospitalisation or emergency institutionalisation. |
| Inclusion criteria |
- Male and female;
- Patient with Alzheimer's-type dementia. |
| Population type | |
| Age |
Elderly (65 to 79 years) Great age (80 years and more) |
| Population covered |
Sick population |
| Gender |
Male Woman |
| Geography area |
National |
| Detail of the geography area | 16 university hospital centres for geriatrics, neurology and psychiatry. |
| Data collection | |
| Dates | |
| Date of first collection (YYYY or MM/YYYY) | 2000 |
| Date of last collection (YYYY or MM/YYYY) | 2002 |
| Size of the database | |
| Size of the database (number of individuals) |
[500-1000[ individuals |
| Details of the number of individuals | 700 |
| Data | |
| Database activity |
Data collection completed |
| Type of data collected |
Declarative data Paraclinical data |
| Declarative data (detail) |
Face to face interview |
| Details of collected declarative data | Case report form: sociodemographic data, medical and surgical history, date of initial symptoms and disease diagnosis age, current list of medication taken, list of different psychotropic or specific disease treatments, ADL and IADL autonomy assessment, overall assessment of cognitive function by MMS and ADAS-Cog, assessment of dementia stage by Reisberg GDS and CDR, assessment of patient's behavioural problems by NPI, nutritional status assessment using MNA, balance disorder assessment (one-leg balance, living arrangement, use of home care service, such housekeeping, home nursing care, private nurse, use of private paid help such a domestic worker, overnight care, cleaning lady, home meal deliveries, allowances received for dependent elderly people (Prestation Spécifique Dépendance [Specific Dependency Benefit], Allocation Personnalisée d'Autonomie [Personal Autonomy Allowance]), sources of income (retirement, family or caregiver support, various allowances, pensions), level of education (level of education, the highest qualification obtained), former occupation(s). |
| Paraclinical data (detail) | - Brain scan - thyroid assessment. |
| Presence of a biobank |
No |
| Health parameters studied |
Health event/morbidity Quality of life/health perception |
| Procedures | |
| Data collection method | Data is collected during visits carried out over 6 months in university hospital centres participating in the study. Data are gathered through a case report form by a medical team trained to administer different tests. |
| Participant monitoring |
Yes |
| Details on monitoring of participants | Follow-up over 4 years. |
| Links to administrative sources |
No |
| Promotion and access | |
| Promotion | |
| Link to the document | http://tinyurl.com/Hal-REAL-FR |
| Description | List of publications in HAL |
| Link to the document | http://www.ncbi.nlm.nih.gov/pubmed/?term=Vellas+B[author]+AND+%28REAL.FR+OR+REAL-FR%29 |
| Description | List of publications in Pubmed |
| Access | |
| Terms of data access (charter for data provision, format of data, availability delay) | Contact the scientist in charge. |
| Access to aggregated data |
Access on specific project only |
| Access to individual data |
Access on specific project only |
