ENGELA - Environment and Adult Lymphoma Genetics 
Head :
Clavel Jacqueline
Last update : 09/05/2017 | Version : 1 | ID : 6142
| General | |
| Identification | |
| Detailed name | Environment and Adult Lymphoma Genetics |
| Sign or acronym | ENGELA |
| CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | CNIL: 998198 |
| General Aspects | |
| Medical area |
Cancer research Hematology Immunology |
| Health determinants |
Genetic |
| Others (details) | Lymphoid tumours, haematopoietic tumours, non-Hodgkin's lymphoma, Hodgkin's lymphoma, multiple myeloma, lymphoproliferative syndrome |
| Keywords | Incidence, genetics, lymphoma |
| Scientific investigator(s) (Contact) | |
| Name of the director | Clavel |
| Surname | Jacqueline |
| Address | 16, Avenue Paul Vaillant-Couturier 94807 VILLEJUIF |
| Phone | +33 (0)1 45 59 50 38 |
| jacqueline.clavel@inserm.fr | |
| Organization | Institut National de la Santé et de la Recherche |
| Collaborations | |
| Participation in projects, networks and consortia |
Yes |
| Funding | |
| Funding status |
Mixed |
| Details | - Association pour la Recherche contre le Cancer - Fondation de France - AFSSET (Agence française de sécurité sanitaire de l'environnement et du travail) - Dons des employés Faberge |
| Governance of the database | |
| Sponsor(s) or organisation(s) responsible | Institut National de la Santé et de la Recherche Médicale |
| Organisation status |
Public |
| Additional contact | |
| Main features | |
| Type of database | |
| Type of database |
Study databases |
| Study databases (details) |
Case control study |
| Database recruitment is carried out by an intermediary |
A selection of health institutions and services |
| Database recruitment is carried out as part of an interventional study |
No |
| Additional information regarding sample selection. | Subjects selected: - lymphoid haemopathy cases - case-controls treated in hospitals |
| Database objective | |
| Main objective | To analyse the relationship between lymphoid malignancies and family history of cancer. |
| Inclusion criteria | - Men or women - aged between 18 and 75 years old |
| Population type | |
| Age |
Adulthood (19 to 24 years) Adulthood (25 to 44 years) Adulthood (45 to 64 years) Elderly (65 to 79 years) |
| Population covered |
Sick population |
| Gender |
Male Woman |
| Geography area |
National |
| Detail of the geography area | France (Hospitals in Bordeaux, Brest, Caen, Nantes, Lille and Toulouse) |
| Data collection | |
| Dates | |
| Date of first collection (YYYY or MM/YYYY) | 2001 |
| Date of last collection (YYYY or MM/YYYY) | 2004 |
| Size of the database | |
| Size of the database (number of individuals) |
[1000-10 000[ individuals |
| Details of the number of individuals | 1586: - 828 cas/cases - 758 témoins/controls |
| Data | |
| Database activity |
Data collection completed |
| Type of data collected |
Clinical data Declarative data Paraclinical data |
| Clinical data (detail) |
Direct physical measures |
| Declarative data (detail) |
Paper self-questionnaire Face to face interview |
| Paraclinical data (detail) | Blood sample |
| Presence of a biobank |
Yes |
| Contents of biobank |
Serum Tissues DNA |
| Details of biobank content | Constitutional DNA, tumour tissue |
| Health parameters studied |
Health event/morbidity Health event/mortality Health care consumption and services |
| Care consumption (detail) |
Hospitalization |
| Procedures | |
| Participant monitoring |
Yes |
| Links to administrative sources |
No |
| Promotion and access | |
| Promotion | |
| Link to the document | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760125/?tool |
| Link to the document | http://oem.bmj.com/content/67/10/664.full.pdf+html |
| Link to the document | http://journals.lww.com/joem/pages/articleviewer.aspx?year |
| Link to the document | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728754/ |
| Link to the document | http://link.springer.com/article/10.1007%2Fs10552-008-9182-1 |
| Link to the document | http://www.nature.com/leu/journal/v21/n9/full/2404738a.html |
| Link to the document | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1853236/ |
| Link to the document | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323431/ |
| Link to the document | http://epi.grants.cancer.gov/InterLymph/ |
| Access | |
| Terms of data access (charter for data provision, format of data, availability delay) | To be defined |
| Access to aggregated data |
Access on specific project only |
| Access to individual data |
Access on specific project only |
