Saturn-Inf 2008-2009 Survey (Enquête Saturn-Inf 2008-2009) - National Survey on Lead Poisoning Prevalence and Infectious Disease Seroprevalence in Children Between 6 Months and 6 Years Old (Lead Poisoning Component and Biobank) 
Head :
Invs-DSE
Last update : 01/01/2019 | Version : 1 | ID : 7596
| General | |
| Identification | |
| Detailed name | National Survey on Lead Poisoning Prevalence and Infectious Disease Seroprevalence in Children Between 6 Months and 6 Years Old (Lead Poisoning Component and Biobank) |
| Sign or acronym | Saturn-Inf 2008-2009 Survey (Enquête Saturn-Inf 2008-2009) |
| CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | CNIL authorisation no. 907160, CCP approval on 10/07/2008 (no. 08-022), AFSSAPS approval no. RCB 2008-A00436-49. |
| General Aspects | |
| Medical area |
Biology Pediatrics |
| Pathology (details) | Housing |
| Health determinants |
Intoxication Lifestyle and behavior Social and psychosocial factors |
| Keywords | blood lead level, exposure, lead poisoning, prevalence, children |
| Scientific investigator(s) (Contact) | |
| Name of the director | Invs-DSE |
| Address | 12, rue du Val d’Osne 94410 |
| DSE-infosan@invs.sante.fr | |
| Organization | Institut de veille sanitaire |
| Collaborations | |
| Funding | |
| Funding status |
Public |
| Details | InVS |
| Governance of the database | |
| Sponsor(s) or organisation(s) responsible | Institut de Veille Sanitaire |
| Organisation status |
Public |
| Additional contact | |
| Main features | |
| Type of database | |
| Type of database |
Study databases |
| Study databases (details) |
Not-repeated cross-sectional studies (except case control studies) |
| Database recruitment is carried out by an intermediary |
A selection of health institutions and services |
| Database recruitment is carried out as part of an interventional study |
No |
| Additional information regarding sample selection. | 2-stage survey: - First stage: random selection of hospitals (hospitals with at least 300 hospitalisations per year for children aged between 6 months and 6 years), double stratification by geographical region (22 metropolitan regions + Martinique + Guadeloupe + Réunion) on the lead exposure risk at home - second stage: complete recruitment of all children hospitalised in the paediatric or paediatric surgery departments and who meet the inclusion criteria. |
| Database objective | |
| Main objective |
- To estimate the national prevalence of lead poisoning in children between 6 months and 6 years old;
- To determine the blood lead level distribution of children between 6 months and 6 years old by administrative region; - To update knowledge of factors that determine blood lead level; - To validate indicators that characterise at-risk areas. |
| Inclusion criteria |
- Children between 6 months and 6 years old;
- Covered by social security health insurance; - Inpatient or outpatient hospital stay during study period; - Where a blood sample was prescribed as part of treatment or where a sampling system (catheter) is already in place; - Residing in France at the time of enrolment. |
| Population type | |
| Age |
Infant (28 days to 2 years) Early childhood (2 to 5 years) Childhood (6 to 13 years) Adolescence (13 to 18 years) |
| Population covered |
General population |
| Gender |
Male Woman |
| Geography area |
National |
| Detail of the geography area | France |
| Data collection | |
| Dates | |
| Date of first collection (YYYY or MM/YYYY) | 2008 |
| Date of last collection (YYYY or MM/YYYY) | 2009 |
| Size of the database | |
| Size of the database (number of individuals) |
[1000-10 000[ individuals |
| Details of the number of individuals | 3,800 |
| Data | |
| Database activity |
Data collection completed |
| Type of data collected |
Declarative data Biological data Administrative data |
| Declarative data (detail) |
Face to face interview |
| Biological data (detail) | Blood lead level |
| Administrative data (detail) | Individual data (child sociodemographic characteristics) + aggregate data (hospital department activity during survey). |
| Presence of a biobank |
Yes |
| Contents of biobank |
Serum |
| Details of biobank content | Serum sample (>=1.5 ml) in cryotube for 1,243 children. Biobank open to the outside for calls for project proposals. |
| Health parameters studied |
Health event/morbidity Health event/mortality |
| Procedures | |
| Data collection method | Face-to-face questionnaire with parents recorded by hospital staff. Two blood samples collected for blood lead level assay and Biobank. Collection managed by service provider. |
| Classifications used | Dictionary of variables. |
| Quality procedure(s) used | Checks for duplicated, missing, outlier and inconsistent data. |
| Participant monitoring |
No |
| Links to administrative sources |
No |
| Promotion and access | |
| Promotion | |
| Link to the document | http://opac.invs.sante.fr/doc_num.php?explnum_id |
| Link to the document | http://opac.invs.sante.fr/doc_num.php?explnum_id |
| Link to the document | http://opac.invs.sante.fr/doc_num.php?explnum_id |
| Access | |
| Terms of data access (charter for data provision, format of data, availability delay) |
Access to results (protocol and report):
http://opac.invs.sante.fr http://www.invs.sante.fr/Dossiers-thematiques/Environnement-et-sante/Saturnisme-chez-l-enfant/Donnees-d-impregnation-de-la-population-francaise-par-le-plomb http://www.invs.sante.fr/Dossiers-thematiques/Environnement-et-sante/Saturnisme-chez-l-enfant/Publications Access to data: individual anonymised data. Application procedures: request to Bénédicte Bérat. Data access procedure generated and held by InVS. |
