- Doubs and Côte d'Or viral hepatitis register
Head :
Minello Anne, Inserm U 866. Faculté de Médecine de Dijon
Last update : 04/12/2012 | Version : 1 | ID : 220
| General | |
| Identification | |
| Detailed name | Doubs and Côte d'Or viral hepatitis register |
| CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | CNIL 906073 |
| General Aspects | |
| Medical area |
General practice Infectious diseases |
| Others (details) | hepatitis, cirrhosis |
| Keywords | B virus C virus incidence |
| Scientific investigator(s) (Contact) | |
| Name of the director | Minello |
| Surname | Anne |
| Address | Inserm U 866. Faculté de Médecine, 7 boulevard Jeanne d’Arc, BP 87900 - 21079 Dijon Cedex |
| Phone | + 33 (0)3 80 39 34 28 |
| anne.minello@chu-dijon.fr | |
| Unit | Inserm U 866. Faculté de Médecine de Dijon |
| Organization | CHU |
| Collaborations | |
| Funding | |
| Funding status |
Public |
| Details | Institut national de la santé et de la recherche médicale - Inserm Institut de veille sanitaire - InVS |
| Governance of the database | |
| Sponsor(s) or organisation(s) responsible | CHU Dijon |
| Organisation status |
Public |
| Additional contact | |
| Main features | |
| Type of database | |
| Type of database |
Morbidity registers |
| Database recruitment is carried out by an intermediary |
A selection of health institutions and services |
| Database recruitment is carried out as part of an interventional study |
No |
| Additional information regarding sample selection. |
Selection of subjects having the required inclusion criteria. Several sources are used to identify cases: - Biology laboratories - Pathological anatomy laboratories - Hepato-gastroenterologists - Infectious disease specialists (public) - Addiction specialists (public) -ALD (chronic disease lists), PMSI (hospital diagnosis-related group database), RSI and MSA health insurance funds |
| Database objective | |
| Main objective |
Register objectives in terms of public health (monitoring, assessment) These concern two different methods: descriptive epidemiology and assessment of healthcare practices. The objective of the first method is health monitoring of B and C viral infections: - study of the detection rates of B and C viral serologies and of their trends over time, - study of the contamination method trends over time, - study of diagnostic techniques (systematic screening, diagnostic approach if biological anomalies or symptoms detected), - assessment of the impact of the change in the B viral vaccination campaign in 1998 on the incidence of acute hepatitis B. In the field of healthcare practice, our objectives are: - study of the arrangements for treating hepatitis B and C in the population in general, - assessment of the impact of consensus conferences and national recommendations of good clinical practice, - analysis of care sectors. Register's objectives in terms of research - Study of the natural history of hepatitis B and C in the cohort formed: causes of death, risk of complications. - Anthropological studies to understand what is hampering the treatment of hepatitis C sufferers and study of the determinants of the diagnosis and care proposal for immigrants suffering from hepatitis B |
| Inclusion criteria | Adults and Children carrying the HBs antigen (HBs Ag) and/or hepatitis C (HCV) antibodies |
| Population type | |
| Age |
Newborns (birth to 28 days) Infant (28 days to 2 years) Early childhood (2 to 5 years) Childhood (6 to 13 years) Adolescence (13 to 18 years) Adulthood (19 to 24 years) Adulthood (25 to 44 years) Adulthood (45 to 64 years) Elderly (65 to 79 years) Great age (80 years and more) |
| Population covered |
Sick population |
| Gender |
Male Woman |
| Geography area |
Departmental |
| French regions covered by the database |
Bourgogne Franche-Comté |
| Detail of the geography area | Côte-d'or et Doubs |
| Data collection | |
| Dates | |
| Date of first collection (YYYY or MM/YYYY) | 1994 |
| Size of the database | |
| Size of the database (number of individuals) |
[1000-10 000[ individuals |
| Details of the number of individuals | 1994-2009: 3750 |
| Data | |
| Database activity |
Data collection completed |
| Type of data collected |
Clinical data Biological data Administrative data |
| Clinical data (detail) |
Direct physical measures |
| Biological data (detail) | B virus C virus incidence |
| Administrative data (detail) | Identification data |
| Presence of a biobank |
No |
| Health parameters studied |
Health event/morbidity Health event/mortality |
| Procedures | |
| Data collection method | Active collection (Dispatches in real time by laboratories and real-time reporting by gastroenterologists) |
| Participant monitoring |
Yes |
| Details on monitoring of participants | Follow-up of the cohort of patients suffering from a B or C viral infection would enable definition of the risk of cirrhosis and primitive liver cancer and identification of the factors that might influence this risk. |
| Links to administrative sources |
Yes |
| Linked administrative sources (detail) | ALD, PMSI, RSI, MSA |
| Promotion and access | |
| Promotion | |
| Link to the document | http://www.ncbi.nlm.nih.gov/pubmed?term |
| Access | |
| Terms of data access (charter for data provision, format of data, availability delay) | national and international congresses, access to the Register's data by request |
| Access to aggregated data |
Access on specific project only |
| Access to individual data |
Access on specific project only |
