- Digestive cancers registry of Burgundy
Head :
Bouvier Anne-Marie, Centre de Recherche INSERM U866
Last update : 04/12/2012 | Version : 1 | ID : 217
| General | |
| Identification | |
| Detailed name | Digestive cancers registry of Burgundy |
| CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | 998024 |
| General Aspects | |
| Medical area |
Cancer research |
| Health determinants |
Geography |
| Others (details) | digestive cancers |
| Keywords | care practice, trends, digestive cancers, epidemiology, public health, survival |
| Scientific investigator(s) (Contact) | |
| Name of the director | Bouvier |
| Surname | Anne-Marie |
| Address | Registre des Cancers, Faculté de Médecine, BP 87900, 21079 Dijon Cedex |
| Phone | + 33 (0)3 80 39 33 38 |
| anne-marie.bouvier@u-bourgogne.fr | |
| Unit | Centre de Recherche INSERM U866 |
| Organization | CHU |
| Collaborations | |
| Funding | |
| Funding status |
Public |
| Details | The National Public Health Institute (InVS) and the National Cancer Institute (INCa) |
| Governance of the database | |
| Sponsor(s) or organisation(s) responsible | University Hospital Dijon |
| Organisation status |
Public |
| Sponsor(s) or organisation(s) responsible | University of Burgundy |
| Organisation status |
Public |
| Additional contact | |
| Main features | |
| Type of database | |
| Type of database |
Morbidity registers |
| Database recruitment is carried out by an intermediary |
A selection of health institutions and services |
| Database recruitment is carried out as part of an interventional study |
No |
| Additional information regarding sample selection. |
Selection of subjects having the required inclusion criteria. Several sources are used to identify cases: - Pathological cytology and anatomy laboratories - Private or public physicians - Screening organization structures - Death certificates - The ALD 30 file (concerning the list of 30 chronic diseases eligible for full cover) - files from the PMSIs (French diagnosis-related group databases) of the départements' healthcare institutions. - medical records |
| Database objective | |
| Main objective |
Objectives of the registry in terms of public health (surveillance, evaluation): 1) determine the main health indicators: Incidence, Prevalence, Survival and their change over time. 2) evaluate medical practices, paying particular attention to elderly subjects, and the trends concerning healthcare quality indicators. - Objectives of the registry in terms of research: 1) determination of at-risk groups and epidemiology of pre-cancerous lesions 2) study of quality of life at population level 3) development of new methodological approaches for survival analysis 4) biological epidemiology through the creation of a population-based tumor bank based to evaluate molecular prognostic markers 5) development of new immunological tests looking for colorectal screening, protein signature 6) medico-economic analysis: cost of colorectal cancer, cost-effectiveness analysis of screening strategies. |
| Inclusion criteria |
Malignant and invasive primary digestive tumors and Malignant non-invasive tumors, called in situ or intra-epithelial, when no invasive tumor of the same histological type or location has previously appeared in the same subject. Incidence calculations only take account of invasive malignant tumors. |
| Population type | |
| Age |
Newborns (birth to 28 days) Infant (28 days to 2 years) Early childhood (2 to 5 years) Childhood (6 to 13 years) Adolescence (13 to 18 years) Adulthood (19 to 24 years) Adulthood (25 to 44 years) Adulthood (45 to 64 years) Elderly (65 to 79 years) Great age (80 years and more) |
| Population covered |
General population |
| Gender |
Male Woman |
| Geography area |
Departmental |
| French regions covered by the database |
Bourgogne Franche-Comté |
| Detail of the geography area | Burgundy region: Côte d'Or and Saône-et-Loire administrative areas ('departements') |
| Data collection | |
| Dates | |
| Date of first collection (YYYY or MM/YYYY) | 1976 |
| Size of the database | |
| Size of the database (number of individuals) |
Greater than 20 000 individuals |
| Details of the number of individuals | 1976- 2008: 37 500 cas/cases |
| Data | |
| Database activity |
Current data collection |
| Type of data collected |
Clinical data Paraclinical data Biological data Administrative data |
| Clinical data (detail) |
Direct physical measures |
| Paraclinical data (detail) | diagnostic assessment, patterns of care |
| Biological data (detail) | methodological coordination of a tumor bank gathering tissue samples of colorectal adenocarcinoma resections in the Côte d'Or département |
| Administrative data (detail) | Identification data |
| Presence of a biobank |
Yes |
| Contents of biobank |
Tissues |
| Details of biobank content | for resected colorectal cancers |
| Health parameters studied |
Health event/morbidity Health event/mortality |
| Procedures | |
| Data collection method | active: the registry itself seeks out information from different sources. |
| Classifications used | international nomenclatures |
| Participant monitoring |
Yes |
| Details on monitoring of participants | Vital status - Active follow-up of colorectal cancers is carried out systematically in search of a progressive recurrence (locoregional recurrence or distant metastasis) or second cancer is recorded. Given that over 80% of these recurring cancers arise in the first three years, follow-up is conducted individually every n+3 years after diagnosis, and n+5 years for resection patients for curative purposes. |
| Links to administrative sources |
Yes |
| Linked administrative sources (detail) | RNIPP |
| Promotion and access | |
| Promotion | |
| Link to the document | http://www.ncbi.nlm.nih.gov/pubmed?term |
| Access | |
| Terms of data access (charter for data provision, format of data, availability delay) | exploitation and dissemination of data by scientific publications and oral communication |
| Access to aggregated data |
Access on specific project only |
| Access to individual data |
Access on specific project only |
