DAIFI: Outcome Following Initiation of In Vitro Fertilisation (Devenir Après Initiation d'un traitement par Fécondation In vitro) - Cohort of Couples Starting In Vitro Fertilisation 
Head :
de La Rochebrochard Elise, Ined – Inserm – University of Paris-Sud 11 (Ined UR14/Inserm CESP 1018)
Last update : 01/01/2020 | Version : 1 | ID : 60036
| General | |
| Identification | |
| Detailed name | Cohort of Couples Starting In Vitro Fertilisation |
| Sign or acronym | DAIFI: Outcome Following Initiation of In Vitro Fertilisation (Devenir Après Initiation d'un traitement par Fécondation In vitro) |
| CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | CNIL authorisation no. 05-1334 |
| General Aspects | |
| Medical area |
Gynecology/ obstetrics Psychology and psychiatry |
| Pathology (details) | Infertility |
| Health determinants |
Lifestyle and behavior Occupation Social and psychosocial factors |
| Keywords | household, in vitro fertilisation, Health events, child, birth, adoption |
| Scientific investigator(s) (Contact) | |
| Name of the director | de La Rochebrochard |
| Surname | Elise |
| Address |
INED 133 boulevard Davout 75020 Paris |
| Phone | +33 (0)1 56 06 21 23 |
| roche@ined.fr | |
| Unit | Ined – Inserm – University of Paris-Sud 11 (Ined UR14/Inserm CESP 1018) |
| Organization | National Institute for Demographic Studies |
| Collaborations | |
| Funding | |
| Funding status |
Public |
| Details | ANR (National Agency for Research) |
| Governance of the database | |
| Sponsor(s) or organisation(s) responsible | Institut National de la Santé et de la Recherche Médicale (National Institute for Health and Medical Research) |
| Organisation status |
Public |
| Sponsor(s) or organisation(s) responsible | Institut National d'Etudes Démographiques (National Institute for Demographic Studies) |
| Organisation status |
Public |
| Presence of scientific or steering committees |
Yes |
| Additional contact | |
| Main features | |
| Type of database | |
| Type of database |
Study databases |
| Study databases (details) |
Cohort study |
| Database recruitment is carried out by an intermediary |
A selection of health institutions and services |
| Database recruitment is is made on the basis of: |
Another treatment or procedure |
| Database recruitment is carried out as part of an interventional study |
No |
| Additional information regarding sample selection. | 6,507 couples who started in vitro fertilisation treatment in 2000-2001-2002 in one of 8 AMP [Assistance Médicale à la Procréation (Medically Assisted Procreation)] centres that participated in the study. |
| Database objective | |
| Main objective |
General aim: To assess the likelihood of long-term parental project fulfilment among a population of couples beginning IVF treatment.
Secondary aim: To assess the cumulative IVF success rate, treatment discontinuation and spontaneous births after stopping IVF treatment. |
| Inclusion criteria |
— female
— adult — started IVF treatment between 2000 and 2002 in one of the IVF centres participating in the study. |
| Population type | |
| Age |
Adulthood (19 to 24 years) Adulthood (25 to 44 years) |
| Population covered |
General population |
| Gender |
Woman |
| Geography area |
National |
| Detail of the geography area | 8 centres throughout France |
| Data collection | |
| Dates | |
| Date of first collection (YYYY or MM/YYYY) | 2000 |
| Date of last collection (YYYY or MM/YYYY) | 2010 |
| Size of the database | |
| Size of the database (number of individuals) |
[1000-10 000[ individuals |
| Details of the number of individuals | 6,507 |
| Data | |
| Database activity |
Data collection completed |
| Type of data collected |
Clinical data Declarative data |
| Details of collected clinical data | Age of the man and woman; cause and duration of infertility; medical treatment; number of in vitro fertilization cycles; information on these cycles (number of eggs retrieved, number of embryos obtained, number of transferred embryos, number of frozen embryos, number of frozen embryo transfers, pregnancy); information about other pregnancies. |
| Declarative data (detail) |
Paper self-questionnaire |
| Details of collected declarative data | The self-administered questionnaire at follow-up collects information on socio-demographic data, outcome of parental project, treatment effects (health, relationship, work, etc.), occurrence of spontaneous pregnancy and adoption. |
| Presence of a biobank |
No |
| Health parameters studied |
Health event/morbidity |
| Procedures | |
| Data collection method | Medical data taken from databases at IVF centres. Postal survey of women involved. |
| Quality procedure(s) used | Implementation of procedures to ensure data anonymity and procedures to ensure data quality and consistency. |
| Participant monitoring |
Yes |
| Monitoring procedures |
Monitoring by contact with the participant (mail, e-mail, telephone etc.) |
| Details on monitoring of participants | Duration of follow-up: 8 years (5 years minimum) |
| Links to administrative sources |
Yes |
| Linked administrative sources (detail) | Patient medical record at the IVF centre. |
| Promotion and access | |
| Promotion | |
| Link to the document | http://www.ncbi.nlm.nih.gov/pubmed/?term=DAIFI+AND+de+La+Rochebrochard+E+[Author] |
| Access | |
| Terms of data access (charter for data provision, format of data, availability delay) | No access. |
| Access to aggregated data |
Access not yet planned |
| Access to individual data |
No access |
