EXPRESA - EXacerbation PREdictive factors in Severe Asthma - Cohort on Predictive Exacerbation Factors in Severe Asthmatics ARCHIVE

Head :
Magnan Antoine, UMR 915: l'Institut du thorax

Last update : 01/01/2020 | Version : 1 | ID : 8817

print
Print
xml
XML

Export to XML

Please choose the format :

pdf
PDF
xml
CSV (Excel)

Export to CSV

What sections do you want to export ?

Métadonnées
Identification
General Aspects
Scientific investigator(s) (Contact)
Collaborations
Funding
Governance of the database
Additional contact
Type of database
Database objective
Population type
Dates
Size of the database
Data
Procedures
Promotion
Access
Select all | Invert selection | No selection

Which version do you want to export ?

send
Send
General
Identification
Detailed name Cohort on Predictive Exacerbation Factors in Severe Asthmatics
Sign or acronym EXPRESA - EXacerbation PREdictive factors in Severe Asthma
CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation CNIL
General Aspects
Medical area Study of allergies
Health determinants Genetic
Medicine
Keywords marker, lymphocyte population, predictive factors
Scientific investigator(s) (Contact)
Name of the director Magnan
Surname Antoine
Address 8 quai Moncousu BP 70721 44007 Nantes Cedex 1
Phone +33 (0)2 28 08 01 26
Email antoine.magnan@univ-nantes.fr ; antoine.magnan@inserm.fr
Unit UMR 915: l'Institut du thorax
Organization CHU Nantes ; Institut national de la santé et de la recherche médicale -
Collaborations
Funding
Funding status Public
Details Interregional PHRC 2007, INSERM programme Avenir
Governance of the database
Sponsor(s) or organisation(s) responsible CHU Nantes
Organisation status Public
Sponsor(s) or organisation(s) responsible Institut national de la santé et de la recherche médicale - Inserm
Organisation status Public
Additional contact
Main features
Type of database
Type of database Study databases
Study databases (details) Cohort study
Database recruitment is carried out by an intermediary A selection of health institutions and services
Database recruitment is carried out as part of an interventional study No
Database objective
Main objective To validate exacerbation prediction in certain lymphocyte populations by comparing markers already identified (NO, EEI), based on factors that do or do not cause infection.
Inclusion criteria - Male and female;
- Adult;
- Severe asthmatic.
Population type
Age Adulthood (19 to 24 years)
Adulthood (25 to 44 years)
Adulthood (45 to 64 years)
Population covered Sick population
Gender Male
Woman
Geography area Regional
French regions covered by the database Pays de la Loire
Detail of the geography area Pays de la Loire - 6 centres.
Data collection
Dates
Date of first collection (YYYY or MM/YYYY) 2007
Date of last collection (YYYY or MM/YYYY) 2010
Size of the database
Size of the database (number of individuals) < 500 individuals
Details of the number of individuals 45
Data
Database activity Data collection completed
Type of data collected Clinical data
Declarative data
Clinical data (detail) Medical registration
Details of collected clinical data Measurement of respiratory function.
Declarative data (detail) Paper self-questionnaire
Details of collected declarative data --
Presence of a biobank No
Health parameters studied Health event/morbidity
Procedures
Data collection method Samples are taken, respiratory function is assessed and questionnaires are completed during each visit. Immunomonitoring is systematically carried out. Exacerbations caused by viral infections shall be documented by testing for main causal viruses. Identifying predictive exacerbation markers in severe asthmatics may subsequently allow the relevance of treatment based on these markers to be tested, with the aim to prevent exacerbations.
Participant monitoring Yes
Details on monitoring of participants Monthly follow-up for one year.
Links to administrative sources No
Promotion and access
Promotion
Access
Terms of data access (charter for data provision, format of data, availability delay) Contact the person in charge.
Access to aggregated data Access on specific project only
Access to individual data Access on specific project only

Partners - FAQ - Contact - Site map - Legal notices - Administration - Updated on December 15 2020 - Version 4.10.05