KBP-CPHG - Cohort of Patients with Primary Bronchial Lung Cancer 
Head :
Grivaux Michel, Pulmonology
Last update : 01/01/2020 | Version : 1 | ID : 73306
| General | |
| Identification | |
| Detailed name | Cohort of Patients with Primary Bronchial Lung Cancer |
| Sign or acronym | KBP-CPHG |
| CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | 2000: CNIL 900019; 2010 CNIL 909479 |
| General Aspects | |
| Medical area |
Cancer research Pneumology |
| Pathology (details) | Primary bronchial lung cancer |
| Health determinants |
Genetic Lifestyle and behavior Pollution Social and psychosocial factors |
| Keywords | general hospitals, adenocarcinoma, bronchopulmonary cancer (BPC), patient treatment, epidemiology |
| Scientific investigator(s) (Contact) | |
| Name of the director | Grivaux |
| Surname | Michel |
| Address | 6-8 rue Saint-Fiacre, BP 218, 77104 Meaux cedex |
| m-grivaux@ch-meaux.fr | |
| Unit | Pulmonology |
| Organization | Meaux Hospital |
| Collaborations | |
| Funding | |
| Funding status |
Mixed |
| Details | Respiratory Health Research, CPHG, AstraZeneca, Boehringer Ingelheim, Chugai, GlaxoSmithKline, Lilly France, Pfizer, Pierre Fabre Oncologie, Pneumologie Développement, Roche, and Sanofi-Aventis |
| Governance of the database | |
| Sponsor(s) or organisation(s) responsible | Collège des Pneumologues des Hôpitaux Généraux |
| Organisation status |
Private |
| Additional contact | |
| Main features | |
| Type of database | |
| Type of database |
Study databases |
| Study databases (details) |
Cohort study |
| Database recruitment is carried out by an intermediary |
A selection of health institutions and services |
| Database recruitment is is made on the basis of: |
Another treatment or procedure |
| Database recruitment is carried out as part of an interventional study |
No |
| Database objective | |
| Main objective |
The main aim is to study patient mortality at 5 years and risk factors. Secondary aims are:
– to describe the characteristics in this patient population, their cancer and treatment methods; – to estimate the survival rate at 1, 4 and 5 years; – to compare data obtained with data from the KBP-2000-CPHG study (same study type, centre and patient recruitment methods, patient inclusion criteria and several common items in both questionnaires). |
| Inclusion criteria | All patients with histological and cytological BPC diagnosed between 01 January and 31 December 2000 and 01 January and 31 December 2010. Patients monitored by the pulmonology unit in one of the general hospitals centres (GHC). |
| Population type | |
| Age |
Adulthood (19 to 24 years) Adulthood (25 to 44 years) Adulthood (45 to 64 years) Elderly (65 to 79 years) Great age (80 years and more) |
| Population covered |
Sick population |
| Gender |
Male Woman |
| Geography area |
National |
| Detail of the geography area | France |
| Data collection | |
| Dates | |
| Date of first collection (YYYY or MM/YYYY) | 2000 |
| Date of last collection (YYYY or MM/YYYY) | 2010 |
| Size of the database | |
| Size of the database (number of individuals) |
[10 000-20 000[ individuals |
| Details of the number of individuals | 2000: 4,669; 2010: 7,051 |
| Data | |
| Database activity |
Data collection completed |
| Type of data collected |
Clinical data Declarative data |
| Clinical data (detail) |
Direct physical measures |
| Details of collected clinical data | BPC diagnostic methods (recruitment, symptoms, radiography, sampling method and sample location that led to diagnosis, date of diagnosis, anatomopathological test); functional status based on Performance Status (PS) score; BPC histological type according to World Health Organisation classification and obtained from histological or cytological results (small-cell carcinoma, adenocarcinoma, squamous-cell carcinoma, large-cell carcinoma, bronchioloalveolar carcinoma); cancer stage at time of diagnosis based on Tumor-Node-Metastasis [TNM] clinical NSCLC classification according to the Mountain criteria; treatment strategies and initial therapy chosen by physician. |
| Declarative data (detail) |
Face to face interview |
| Details of collected declarative data | Social and demographic data (age, sex, socio-professional category [INSEE socio-professional categories] and suspected work-related cancer); smoking (number of pack years, duration, any smoking cessation and stop date). |
| Presence of a biobank |
No |
| Health parameters studied |
Health event/morbidity Health event/mortality Health care consumption and services |
| Procedures | |
| Data collection method | By participating physicians. |
| Participant monitoring |
Yes |
| Monitoring procedures |
Monitoring by contact with the referring doctor |
| Details on monitoring of participants | Follow-up at 1, 4 and 5 years (date and cause of death of deceased patients and date of last actual contact with living patients were stated in each record). |
| Links to administrative sources |
No |
| Promotion and access | |
| Promotion | |
| Link to the document | http://www.ncbi.nlm.nih.gov/pubmed/?term=KBP+AND+CPHG |
| Access | |
| Terms of data access (charter for data provision, format of data, availability delay) | Contact the scientist in charge. |
| Access to aggregated data |
Access on specific project only |
| Access to individual data |
Access on specific project only |
