MINOS - Characterisation of Age-Related Bone Loss in Men

Head :
Delmas Pierre, U831

Last update : 07/07/2015 | Version : 2 | ID : 60066

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Métadonnées
Identification
General Aspects
Scientific investigator(s) (Contact)
Collaborations
Funding
Governance of the database
Additional contact
Type of database
Database objective
Population type
Dates
Size of the database
Data
Procedures
Promotion
Access
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General
Identification
Detailed name Characterisation of Age-Related Bone Loss in Men
Sign or acronym MINOS
CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation CNIL 1288625
General Aspects
Medical area Geriatrics
Rheumatology
Health determinants Genetic
Nutrition
Keywords Observed health events, muscle mass, osteoporosis, fractures, clinical risk factors, falls, physical activity
Scientific investigator(s) (Contact)
Name of the director Delmas
Surname Pierre
Email delmas@lyon.inserm.fr
Unit U831
Organization INSERM - Institut National de la Santé et de la Recherche
Collaborations
Participation in projects, networks and consortia Yes
Funding
Funding status Mixed
Details COMMUNAUTE EUROPEENNE (PROJET NEMO) MSD, PMO
Governance of the database
Sponsor(s) or organisation(s) responsible Institut National de la Santé et de la Recherche Médicale
Organisation status Public
Additional contact
Main features
Type of database
Type of database Study databases
Study databases (details) Cohort study
Database recruitment is carried out by an intermediary A population file
Database recruitment is carried out as part of an interventional study No
Additional information regarding sample selection. Inclusion method: Prospective Other bodies active in creating this cohort: SSMB
Database objective
Main objective General objective: A prospective evaluation characterising age-related bone loss in men at different skeletal sites. Identification of clinical, biochemical and hormonal determinants of bone loss and fractures with the aid of biochemical markers.
Inclusion criteria Men aged 19 to 85 years old affiliated with the Burgundy Mine Workers' Welfare Society at Monceau-les-Mines (Saône-et-Loire 71)
Population type
Age Adulthood (19 to 24 years)
Adulthood (25 to 44 years)
Adulthood (45 to 64 years)
Elderly (65 to 79 years)
Population covered General population
Gender Male
Geography area Local
French regions covered by the database Bourgogne Franche-Comté
Detail of the geography area MONCEAU-LES-MINES AND NEIGHBOURING COMMUNES (SAONE-ET-LOIRE 71)
Data collection
Dates
Date of first collection (YYYY or MM/YYYY) 01/1996
Date of last collection (YYYY or MM/YYYY) 01/2006
Size of the database
Size of the database (number of individuals) [1000-10 000[ individuals
Details of the number of individuals 1040
Data
Database activity Current data collection
Type of data collected Clinical data
Declarative data
Paraclinical data
Biological data
Clinical data (detail) Direct physical measures
Medical registration
Declarative data (detail) Face to face interview
Paraclinical data (detail) Imaging
Biological data (detail) Type of samples taken: Bone remodelling markers, sex steroid hormones, parathyroid hormone, vitamin D, IGF1 growth factors
Presence of a biobank Yes
Contents of biobank Whole blood
Serum
Plasma
Fluids (saliva, urine, amniotic fluid, …)
Details of biobank content Serum bank, plasma bank, WHOLE BLOOD, URINE - 1ST MICTURITION AND 24 HOURS (UNTIL FOLLOW-UP 4)
Health parameters studied Health event/morbidity
Health event/mortality
Procedures
Data collection method Interview: Input from a paper questionnaire (Manual input) with double data entry Clinical examinations: Handwritten (Manual input) with double data entry
Participant monitoring Yes
Details on monitoring of participants Follow-up duration: 10 years
Links to administrative sources Yes
Linked administrative sources (detail) SSNB: AFFLIATE DATABASE
Promotion and access
Promotion
Link to the document http://www.ncbi.nlm.nih.gov/pubmed/?term=%28minos+AND+%28Delmas[Author]+OR+Chapurlat+RD[Author]%29%29+OR+11547899[uid]
Description List of publications in Pubmed
Access
Terms of data access (charter for data provision, format of data, availability delay) Data may be used by academic teams Data may be used by industrial teams
Access to aggregated data Access on specific project only
Access to individual data Access on specific project only

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