Cancerology - Cancerology: real-world patient database in oncology & onco-hematology
Head :
Geneviève Bonnelye, Health division
Last update : 09/10/2020 | Version : 1 | ID : 73432
| General | |
| Identification | |
| Detailed name | Cancerology: real-world patient database in oncology & onco-hematology |
| Sign or acronym | Cancerology |
| CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | French Cancerology database is conducted as part of the commitment of the MR-004 reference methodology which covers the data processing and delivered by the French Data Protection Authority (CNIL) with the authorization number n°2204473 v 0 |
| General Aspects | |
| Medical area |
Cancer research Hematology Rare diseases |
| Pathology (details) | Oncology (solid and non-solid tumours) |
| Health determinants |
Addictions Genetic Geography Healthcare system and access to health care services Lifestyle and behavior Medicine Nutrition Pollution Social and psychosocial factors |
| Keywords | Oncology, solid tumour, non-solid tumour, liquid tumour, patient characteristics, treatment sequencing, haematology, clinical profile, biomarker, chemotherapy, targeted therapy, safety, comorbidities |
| Scientific investigator(s) (Contact) | |
| Name of the director | Geneviève |
| Surname | Bonnelye |
| Address |
3 avenue Pierre Masse 75014 Paris |
| Phone | +33 1 40 92 47 58 |
| genevieve.bonnelye@kantar.com | |
| Unit | Health division |
| Organization | Kantar Health division |
| Collaborations | |
| Participation in projects, networks and consortia |
No |
| Funding | |
| Funding status |
Private |
| Details | Syndicated database funded by multiple client subscriptions |
| Governance of the database | |
| Sponsor(s) or organisation(s) responsible | Kantar Health division SAS |
| Organisation status |
Private |
| Presence of scientific or steering committees |
No |
| Additional contact | |
| Name of the contact | Hélène |
| Surname | Chalubert |
| Address |
3 avenue Pierre Masse 75014 Paris |
| Phone | +33 1 40 92 24 33 |
| Helene.Chalubert@kantar.com | |
| Unit | Health division |
| Organization | Kantar Health division |
| Name of the contact | Cécile |
| Surname | Pacheco |
| Address |
3 avenue Pierre Masse 75014 Paris |
| Phone | +33 7 50 12 72 80 |
| Cecile.PACHECO@kantar.com | |
| Unit | Health division |
| Organization | Kantar Health division |
| Main features | |
| Type of database | |
| Type of database |
Study databases |
| Study databases (details) |
Repeated cross-sectional studies (except case control studies) |
| Database recruitment is carried out by an intermediary |
A selection of health care professionals A selection of health institutions and services |
| Database recruitment is carried out as part of an interventional study |
No |
| Additional information regarding sample selection. |
Cancerology database uses a 2-stage clustered sampling process with:
- firstly a screening phase to identify the sites and medical wards involved in the management of cancer patients - secondly an intensive phase to update the database via an extraction of patient-level data by participating physicians, directly from medical charts. 40-80 physicians are involved in the database update (per tumour and country) representing 100-400 case report forms (per tumour and country). Possibility for extra case report forms. |
| Database objective | |
| Main objective |
To determine the epidemiology, patient & tumour characterstics, biomarkers, detailed treatment patterns, safety, and clinical outcomes across 25+ solid and non-solid tumours in France, Germany, Italy, Spain and the UK.
|
| Inclusion criteria | Patients currently receiving active anti-tumour drug treatment. |
| Population type | |
| Age |
Adulthood (19 to 24 years) Adulthood (25 to 44 years) Adulthood (45 to 64 years) Elderly (65 to 79 years) Great age (80 years and more) |
| Population covered |
Sick population |
| Pathology | C00-C97 - Malignant neoplasms |
| Gender |
Male Woman |
| Geography area |
International |
| Detail of the geography area | France, Germany, Italy, Spain, UK |
| Data collection | |
| Dates | |
| Date of first collection (YYYY or MM/YYYY) | 1993 |
| Date of last collection (YYYY or MM/YYYY) | 2020 |
| Size of the database | |
| Size of the database (number of individuals) |
[1000-10 000[ individuals |
| Details of the number of individuals | Please contact Kantar Health division directly. |
| Data | |
| Database activity |
Data collection completed |
| Type of data collected |
Clinical data Declarative data Biological data |
| Clinical data (detail) |
Medical registration |
| Details of collected clinical data | Patient characteristics, clinical profile, tumour characteristics, safety, clinical outcomes |
| Declarative data (detail) |
Paper self-questionnaire |
| Details of collected declarative data | Patient count |
| Biological data (detail) | Biomarkers |
| Presence of a biobank |
No |
| Health parameters studied |
Health event/morbidity Others |
| Procedures | |
| Data collection method | Face-to-face self-administered questionnaire and case report forms |
| Quality procedure(s) used | ISO 20252 |
| Participant monitoring |
No |
| Followed pathology | |
| Links to administrative sources |
No |
| Promotion and access | |
| Promotion | |
| Link to the document | E. Manna, K. Kikuchi , H. Chalubert , I. Amri, P. Medina. BRAF mutation testing and results among French patients with solid tumours. Poster to be presented at ESMO 2020. |
| Link to the document | Bassila L, Medina P, Chalubert H. Trends in anti-emetic drug use in hematology-oncology based on Cancerology data in France. Poster to be presented at ISPOR US 2020. |
| Link to the document | Klein AB, Wand H, Shire N, Chalubert H, Alessandrini ER, Descoins S, Medina P Treatment Patterns in Head and Neck Squamous Cell Cancer in France: ARTISTE Study of Cancerology Patient Charts. Value Health. 2017 Oct-Nov;20:A419 |
| Link to the document | Medina P, Chalubert H, Pezic N, Wiegand J, Brihaye H, Spitzer M Epidemiologic burden of pulmonary metastasis in France. Value Health May 2019Volume 22, Supplement 2, Page S84. |
| Link to the document | Klein AB, Wand H, Shire N, Chalubert H, Alessandrini ER, Descoins S, Medina P Treatment patterns in non-small cell lung cancer in France: ARTISTE study of Cancerology patient charts. Value Health. 2017 Oct-Nov;20:A419 |
| Link to the document | Colomer R, Hall P, Szkultecka-Debek M, Bondi RC, Flinois A, Auziere S, Le Cléac'h JY. Real-world treatment in patients with HER2+ metastatic breast cancer: Treatment decisions in HER2+ mBC. Breast Cancer Res Treat. 2018 Feb;168(1):197-205. doi: 10.1007/s10549-017-4567-z. |
| Link to the document | Chabernaud H, Descoins S, Flinois A, Real-world studies in Onco-hematology: which parameter should be used to measure the efficacy of treatments, poster presented at ISPOR EU 2019. |
| Link to the document | Chabernaud H, Bonnelye G, Flinois A, French physician sensitivity to and consideration of the costs of cancer treatment, poster presented at ISPOR EU 2015. |
| Link to the document | Flinois A, Bonnelye G, Chabernaud H, Evolution of the number of patients treated for metastatic cancer between 2003 and 2013 in France, poster presented at ISPOR EU 2015. |
| Access | |
| Presence of document that lists variables and coding procedures |
Yes |
| Terms of data access (charter for data provision, format of data, availability delay) | Please contact Kantar Health division directly. |
| Access to aggregated data |
Access on specific project only |
| Access to individual data |
No access |
