IBIS - Post-critical immunosuppression in intensive care patients - Immunity after Brain Injury Study
Head :
ROQUILLY Antoine
Last update : 04/27/2021 | Version : 1 | ID : 73966
| General | |
| Identification | |
| Detailed name | Post-critical immunosuppression in intensive care patients - Immunity after Brain Injury Study |
| Sign or acronym | IBIS |
| CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | DC-2017-2987 |
| General Aspects | |
| Medical area |
Anesthesiology – Intensive care |
| Study in connection with Covid-19 |
Yes |
| Pathology (details) | COVID, injury, sepsis, pneumonia, brain death, extracorporeal circulation |
| Health determinants |
Healthcare system and access to health care services |
| Keywords | biocollection |
| Scientific investigator(s) (Contact) | |
| Name of the director | ROQUILLY |
| Surname | Antoine |
| Address | Service d'anesthésie-réanimation - Hôtel Dieu - CHU de Nantes |
| Phone | 0253482230 |
| Collaborations | |
| Participation in projects, networks and consortia |
Yes |
| Details | Altanrea network, HAP² consortium |
| Funding | |
| Funding status |
Public |
| Governance of the database | |
| Sponsor(s) or organisation(s) responsible | Nantes University Hospital - Research Promotion |
| Organisation status |
Public |
| Presence of scientific or steering committees |
Yes |
| Additional contact | |
| Name of the contact | Flattres |
| Surname | Delphine |
| Address | Service d'anesthésie-réanimation - Hôtel Dieu CHU de Nantes - 1 place Alexis Ricordeau - 44093 Nantes Cedex 1 |
| Phone | 0253482308 |
| delphine.flattresduchaussoy@chu-nantes.fr | |
| Main features | |
| Type of database | |
| Type of database |
Others |
| Specify | Cohort and biocollection |
| Database recruitment is carried out by an intermediary |
A selection of health institutions and services |
| Database recruitment is is made on the basis of: |
Another treatment or procedure |
| Additional information regarding sample selection. | Prospective follow-up with biocollection on a cohort of intensive care patients |
| Database objective | |
| Main objective |
The primary objective of this cohort with biocollections is to describe the epidemiology of medical complications arising during hospitalisation in an intensive care unit
|
| Inclusion criteria |
All patients admitted to the surgical intensive care units at Nantes University Hospital, fulfilling the following
inclusion criteria: 1. Hospitalisation in intensive care > 48 hours 2. Aged over 15 years 3. Reason for hospitalisation including: a. Severe injury with the need for mechanical ventilation > 24 hours b. Acute brain injury with the need for mechanical ventilation > 24 hours c. Septic shock |
| Population type | |
| Age |
Adulthood (19 to 24 years) Adulthood (25 to 44 years) Adulthood (45 to 64 years) Elderly (65 to 79 years) |
| Population covered |
Sick population |
| Pathology | J12 - Viral pneumonia, not elsewhere classified |
| S00-S09 - Injuries to the head | |
| R57 - Shock, not elsewhere classified | |
| A41 - Other sepsis | |
| T00-T07 - Injuries involving multiple body regions | |
| S06 - Intracranial injury | |
| I61 - Intracerebral haemorrhage | |
| I64 - Stroke, not specified as haemorrhage or infarction | |
| Gender |
Male Woman |
| Geography area |
Local |
| French regions covered by the database |
Pays de la Loire |
| Data collection | |
| Dates | |
| Date of first collection (YYYY or MM/YYYY) | 2013 |
| Size of the database | |
| Size of the database (number of individuals) |
[500-1000[ individuals |
| Data | |
| Database activity |
Current data collection |
| Type of data collected |
Clinical data Paraclinical data Biological data Administrative data |
| Clinical data (detail) |
Direct physical measures Medical registration |
| Presence of a biobank |
Yes |
| Contents of biobank |
Serum Plasma Blood cells isolated Fluids (saliva, urine, amniotic fluid, …) Others |
| Details of biobank content | PBMC, tracheal aspiration, skin and rectal swabs |
| Procedures | |
| Data collection method | eCRF |
| Participant monitoring |
Yes |
| Monitoring procedures |
Monitoring by convocation of the participant |
| Promotion and access | |
| Promotion | |
| Access | |
| Access to aggregated data |
Access on specific project only |
| Access to individual data |
Access on specific project only |
