ITMO public health
Last update : 02/12/2016 | Version : 1 | ID : 73290
| General | |
| Identification | |
| Detailed name | Epidemiological Study on the Relationship Between Respiratory Health and Air Pollution From Industrial Sources |
| Sign or acronym | ELISABET |
| CNIL registration number, number and date of CPP agreement, AFSSAPS (French Health Products Safety Agency) authorisation | local ethical committee (CPP Nord Ouest IV) identifier: 2010-A00065-34) |
| General Aspects | |
| Medical area |
Cardiology Pneumology |
| Pathology (details) | obstructive ventilatory disorders, asthma, chronic obstruction |
| Health determinants |
Climate Geography Lifestyle and behavior Pollution |
| Keywords | industrial air pollutant, functional tests lung |
| Scientific investigator(s) (Contact) | |
| Name of the director | Dauchet |
| Surname | Luc |
| Address |
1 rue du Professeur Calmette BP 245 59019 Lille Cedex |
| Phone | +33 (0)3 20 87 72 87 |
| Luc.dauchet@pasteur-lille.fr | |
| Unit | Service d'Epidémiologie et de Santé Publique Hôpital Calmette - Centre Hospitalier et Universitaire de Lille |
| Organization | Institut Pasteur de Lille |
| Collaborations | |
| Participation in projects, networks and consortia |
Yes |
| Details | NCD Risk Factor Collaboration (NCD-RisC). |
| Funding | |
| Funding status |
Public |
| Details | funded by the Nord Pas-de-Calais Regional Council and the European Regional Development Fund (ERDF-FEDER Presage N°36034) as part of the CPER Institut de Recherche en ENvironnement Industriel (IRENI) program |
| Governance of the database | |
| Sponsor(s) or organisation(s) responsible | CHRU de Lille |
| Organisation status |
Public |
| Presence of scientific or steering committees |
Yes |
| Additional contact | |
| Main features | |
| Type of database | |
| Type of database |
Study databases |
| Study databases (details) |
Not-repeated cross-sectional studies (except case control studies) |
| Database recruitment is carried out by an intermediary |
A population file |
| Database recruitment is carried out as part of an interventional study |
No |
| Additional information regarding sample selection. | Participants were selected from electoral rolls of Dunkirk and Lille by random sampling. |
| Database objective | |
| Main objective | To compare the prevalence of the obstructive ventilatory disorders (OVD) in the Urban Community of Dunkirk touched by the industrial pollution in relation to the one recovered in the Urban Community of Lille less industrialized. |
| Inclusion criteria |
- men and women
- 40 years to 64 years - living in the Urban Community of Dunkirk or in the Urban Community of Lille |
| Population type | |
| Age |
Adulthood (25 to 44 years) Adulthood (45 to 64 years) |
| Population covered |
General population |
| Gender |
Male Woman |
| Geography area |
Local |
| French regions covered by the database |
Nord - Pas-de-Calais Picardie |
| Detail of the geography area | Dunkirk and Lille |
| Data collection | |
| Dates | |
| Date of first collection (YYYY or MM/YYYY) | 01/2011 |
| Date of last collection (YYYY or MM/YYYY) | 11/2013 |
| Size of the database | |
| Size of the database (number of individuals) |
[1000-10 000[ individuals |
| Details of the number of individuals | 3276 |
| Data | |
| Database activity |
Data collection completed |
| Type of data collected |
Clinical data Declarative data Biological data |
| Clinical data (detail) |
Medical registration |
| Details of collected clinical data | spirometry testing, functional tests lung, Blood pressure |
| Declarative data (detail) |
Paper self-questionnaire Face to face interview |
| Biological data (detail) | lipids, glycemia, HBA1C, Blood metals, standard bilogical analysis |
| Presence of a biobank |
Yes |
| Contents of biobank |
Serum Plasma Fluids (saliva, urine, amniotic fluid, …) DNA |
| Details of biobank content | A 2 ml aliquot of heparinized plasma stored at -20 ° C, five 0.5 ml aliquots of EDTA plasma stored at -80 ° C, two 1-ml aliquots of EDTA blood stored at -80 ° C, an aliquot of 10 ml and three aliquots of 5 ml of urine stored at -80 ° C, two locks of hair preserved in an envelope at room temperature, six 0.250 ml aliquots of condensate stored at -80 ° C, DNA extraction. |
| Health parameters studied |
Health event/morbidity |
| Procedures | |
| Data collection method | Data was collected at home. In all cases, a trained, registered nurse administered a detailed questionnaire and performed spirometry testing. |
| Participant monitoring |
No |
| Links to administrative sources |
No |
| Promotion and access | |
| Promotion | |
| Link to the document | https://clinicaltrials.gov/ct2/show/NCT02490553 |
| Description | Epidemiological Study on the Relationship Between Respiratory Health and Air Pollution From Industrial Sources (ELISABET) |
| Link to the document | http://www.ncbi.nlm.nih.gov/pubmed/26564001 |
| Description | Prevalence and underdiagnosis of airway obstruction among middle-aged adults in northern France: The ELISABET study 2011-2013. |
| Access | |
| Presence of document that lists variables and coding procedures |
Yes |
| Terms of data access (charter for data provision, format of data, availability delay) |
possibility to propose Ancillary study after validation by the steering comity.
Contact the Principal investigator : luc.dauchet@pasteur-lille.fr |
| Access to aggregated data |
Access on specific project only |
| Access to individual data |
Access on specific project only |
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